Cover Image

Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii

Goniothalamin produced by the Malaysian medicinal plant, Goniothalamus andersonii J. Sinclair, strongly inhibits plant growth. However, its mode of action has not been characterized at the gene expression level. We conducted DNA microarray assay to analyze the changes in early gene responses of Arab...

Full description

Saved in:
Bibliographic Details
Main Authors: Wasano, Naoya, Takemura, Tomoko, Ismil, Raihan, Bakar, Baki, Fujii, Yoshiharu
Format: Article
Published: SAGE Publications 2015
Subjects:
Q Science (General)
QH Natural history
Online Access:http://eprints.um.edu.my/19470/
https://doi.org/10.1177/1934578X1501000507
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.um.eprints.19470
record_format eprints
spelling my.um.eprints.194702020-01-29T02:12:18Z http://eprints.um.edu.my/19470/ Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii Wasano, Naoya Takemura, Tomoko Ismil, Raihan Bakar, Baki Fujii, Yoshiharu Q Science (General) QH Natural history Goniothalamin produced by the Malaysian medicinal plant, Goniothalamus andersonii J. Sinclair, strongly inhibits plant growth. However, its mode of action has not been characterized at the gene expression level. We conducted DNA microarray assay to analyze the changes in early gene responses of Arabidopsis thaliana seedlings. After a 6-h exposure to goniothalamin, we observed an upregulation of genes highly associated with heat response, and 22 heat shock protein (AtHSP) genes were upregulated more than 50 fold. Together with these genes, we observed upregulation of the genes related to oxidative stress and protein folding. Also, the genes related to cell wall modification and cell growth, expansin (AtEXPA) genes, were significantly downregulated. The results suggested that goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings. SAGE Publications 2015 Article PeerReviewed Wasano, Naoya and Takemura, Tomoko and Ismil, Raihan and Bakar, Baki and Fujii, Yoshiharu (2015) Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii. Natural Product Communications, 10 (5). pp. 725-727. ISSN 1934-578X https://doi.org/10.1177/1934578X1501000507 doi:10.1177/1934578X1501000507
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QH Natural history
spellingShingle Q Science (General)
QH Natural history
Wasano, Naoya
Takemura, Tomoko
Ismil, Raihan
Bakar, Baki
Fujii, Yoshiharu
Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
description Goniothalamin produced by the Malaysian medicinal plant, Goniothalamus andersonii J. Sinclair, strongly inhibits plant growth. However, its mode of action has not been characterized at the gene expression level. We conducted DNA microarray assay to analyze the changes in early gene responses of Arabidopsis thaliana seedlings. After a 6-h exposure to goniothalamin, we observed an upregulation of genes highly associated with heat response, and 22 heat shock protein (AtHSP) genes were upregulated more than 50 fold. Together with these genes, we observed upregulation of the genes related to oxidative stress and protein folding. Also, the genes related to cell wall modification and cell growth, expansin (AtEXPA) genes, were significantly downregulated. The results suggested that goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.
format Article
author Wasano, Naoya
Takemura, Tomoko
Ismil, Raihan
Bakar, Baki
Fujii, Yoshiharu
author_facet Wasano, Naoya
Takemura, Tomoko
Ismil, Raihan
Bakar, Baki
Fujii, Yoshiharu
author_sort Wasano, Naoya
title Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
title_short Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
title_full Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
title_fullStr Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
title_full_unstemmed Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii
title_sort transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the malaysian medicinal plant goniothalamus andersonii
publisher SAGE Publications
publishDate 2015
url http://eprints.um.edu.my/19470/
https://doi.org/10.1177/1934578X1501000507
_version_ 1657488191580536832
score 13.211869

Similar Items