Cover Image

Renal targeting potential of a polymeric drug carrier, poly-L-glutamic acid, in normal and diabetic rats

Background and purpose: Poly-l-glutamic acid (PG) has been used widely as a carrier to deliver anticancer chemotherapeutics. This study evaluates PG as a selective renal drug carrier. Experimental approach: 3H-deoxycytidine-labeled PGs (17 or 41 kDa) and 3H-deoxycytidine were administered intravenou...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chai, H.J., Kiew, L.V., Chin, Y., Norazit, A., Noor, S.M., Lo, Y.L., Looi, C.Y., Lau, Y.S., Lim, T.M., Wong, W.F., Abdullah, N.A., Sattar, M.Z.A., Johns, E.J., Chik, Z., Chung, L.Y.
Format:	Article
Published:	Dove Medical Press 2017
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/19216/ http://dx.doi.org/10.2147/IJN.S111284
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Effect of TGF-β1 antisense oligodeoxynucleotide on renal function in chronic renal failure rats
by: Law, C.H., et al.
Published: (2008)

Efficacy of a Poly-L-Glutamic acid-gemcitabine conjugate in tumor-bearing mice
by: Kiew, L.V., et al.
Published: (2012)

Effect of TGF-beta 1 antisense oligodeoxynucleotide on renal function in chronic renal failure rats
by: Hiong, L.C., et al.
Published: (2008)

Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia–reperfusion injury in the anaesthetised rat
by: Kiew, L.V., et al.
Published: (2004)

Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia–reperfusion injury in the anaesthetised rat
by: Kiew, L.V., et al.
Published: (2004)

Role of the renal sympathetic nervous system in mediating renal ischaemic injury-induced reductions in renal haemodynamic and excretory functions
by: Salman, I.M., et al.
Published: (2010)

Role of renal sympathetic nervous system in the control of renal potassium handling
by: Salman, I.M., et al.
Published: (2010)

Interpretation of morphological descriptors on nanocellulose from oil palm frond fibers under weak acid, strong acid, and enzymatic treatments
by: Kong, Y.L., et al.
Published: (2023)

Effect of carvedilol and losartan on renal responses to ang ii and adrenergic agonists in fructose-fed rat
by: Abdulla, M.H., et al.
Published: (2010)

Acute renal failure following multiple wasp stings
by: Thiruventhiran, T., et al.
Published: (1999)

Sympathetic nervous system interacts with renin-angiotensin system to control renal sodium and water handling in SHR rat
by: Salman, I.M., et al.
Published: (2010)

Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-γ), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats
by: Afzal, S., et al.
Published: (2016)

Role of norepinephrine & angiotensin II in the neural control of renal sodium & water handling in spontaneously hypertensive rats
by: Salman, I.M., et al.
Published: (2010)

Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia-reperfusion injury in the anaesthetised rat
by: Kiew, Lik Voon, et al.
Published: (2004)

Acute oral toxicity of methanolic seed extract of cassia fistula in mice
by: Jothy, S.L., et al.
Published: (2011)

T-cell receptor signaling induces proximal Runx1 transactivation via a calcineurin–NFAT pathway
by: Wong, W.F., et al.
Published: (2014)

Membrane support formulation and carrier selection in supported liquid membrane for extraction of zwitterionic form of Glutamic acid
by: Vikneswary, Rajendaran, et al.
Published: (2021)

Genetic and Chromosomal Aberrations and Their Clinical Significance in Renal Neoplasms
by: Yap, N.Y., et al.
Published: (2015)

Choline chloride (ChCl) and monosodium glutamate (MSG)-based green solvents from optimized cactus malic acid for biomass delignification
by: Yiin, C.L., et al.
Published: (2017)

Bioassay-directed isolation of active compounds with antiyeast activity from a cassia fistula seed extract
by: Jothy, S.L., et al.
Published: (2011)

Formulation and characterization of nanostructured lipid carrier encapsulate lemongrass oil using ultrasonication technique
by: Ma, J. Y., et al.
Published: (2021)

Erratum: Constraints on the dark matter neutralinos from the radio emissions of galaxy clusters
by: Kiew, C.Y., et al.
Published: (2017)

Urban Farming Prototype Design and Development with IoT System using STEMSEL and Runlinc IDE
by: Chua Y.L., et al.
Published: (2024)

Renal haemodynamic regulation in normotensive wky rats: Effects of sympathectomy and losartan
by: Fathihah, B., et al.
Published: (2007)

Occurrence and molecular characterization of Aspergillus species in beach sand
by: Teh, L.Y., et al.
Published: (2015)

Toxoplasma gondii: Serological characterization and immunogenicity of recombinant surface antigen 2 (SAG2) expressed in the yeast Pichia pastoris
by: Lau, Y.L., et al.
Published: (2008)

Recombinant expression of the larval excretory-secretory antigen TES-120 of Toxocara canis in the methylotrophic yeast Pichia pastoris
by: Fong, M.Y., et al.
Published: (2004)

Acute oral toxicity and brine shrimp lethality of elaeis guineensis Jacq., (Oil Palm Leaf) methanol extract
by: Syahmi, A.R.M., et al.
Published: (2010)

Low dose monosodium glutamate induced oxidative damage and histopathological changes on the renal of male rats
by: Siti Fathiah Masre,, et al.
Published: (2019)

Screening of concurrent alpha-Thalassaemia 1 in beta-Thalassaemia carriers
by: Chong, Y.M., et al.
Published: (2006)

Study on biohydrogen production using different type of carrier materials in attached growth system
by: Ashah M.A., et al.
Published: (2023)

BODIPY dyes in photodynamic therapy
by: Kamkaew, A., et al.
Published: (2013)

Education from a grassroots perspective
by: Ching, L.Y.
Published: (1983)

Antioxidant profiles of a prepared extract of Chinese herbs for the treatment of atopic eczema
by: Chung, L.Y.
Published: (2008)

IDD personalization framework for e-learning
by: Por, L.Y.
Published: (2007)

Multigrid solver for 2D heat conduction problems
by: Koh Y.Y., et al.
Published: (2023)

Internal competition in engineering education�a case study of project design competition in UNITEN
by: Chua Y.L., et al.
Published: (2023)

Rapid Transition from Offline to Online: The Teaching and Learning Experience in Engineering Education
by: Koh Y.Y., et al.
Published: (2024)

A Review of SEAAIR Annual Conferences 2007 � 2021
by: Koh Y.Y., et al.
Published: (2024)

Disseminated nocardiosis with bilateral intraocular involvement in a renal allograft patient
by: Tan, S.Y., et al.
Published: (2000)