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An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja

In order to facilitate/expedite the production of effective and affordable snake antivenoms, a novel in vitro potency assay was previously developed. The assay is based on an antiserum's ability to bind to postsynaptic neurotoxin (PSNT) and thereby inhibit the PSNT binding to the nicotinic acet...

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Bibliographic Details
Main Authors: Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K.Y., Chantrathonkul, B., Eursakun, S., Tan, C.H.
Format: Article
Language:English
Published: Nature Publishing Group 2018
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/18981/1/An_in_vitro_potency_assay_using_nicotinic_acetylcholine_receptor_binding_works_well_with_antivenoms_against_Bungarus_candidus_and_Naja_naja.pdf
http://eprints.um.edu.my/18981/
http://dx.doi.org/10.1038/s41598-018-27794-3
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http://eprints.um.edu.my/18981/1/An_in_vitro_potency_assay_using_nicotinic_acetylcholine_receptor_binding_works_well_with_antivenoms_against_Bungarus_candidus_and_Naja_naja.pdf
http://eprints.um.edu.my/18981/
http://dx.doi.org/10.1038/s41598-018-27794-3

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