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Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes

Abstract Additive manufacturing methods such as three-dimensional printing (3DP) show a great potential for production of porous structure with complex internal and external structures for bone tissue engineering applications. To optimize the 3DP manufacturing process and to produce 3D printed parts...

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Main Authors:	Asadi-Eydivand, M., Solati-Hashjin, M., Farzad, A., Abu Osman, Noor Azuan
Format:	Article
Published:	Elsevier 2016
Subjects:	R Medicine TA Engineering (General). Civil engineering (General)
Online Access:	http://eprints.um.edu.my/18342/ https://doi.org/10.1016/j.rcim.2015.06.005
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spelling	my.um.eprints.183422019-02-07T07:43:45Z http://eprints.um.edu.my/18342/ Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes Asadi-Eydivand, M. Solati-Hashjin, M. Farzad, A. Abu Osman, Noor Azuan R Medicine TA Engineering (General). Civil engineering (General) Abstract Additive manufacturing methods such as three-dimensional printing (3DP) show a great potential for production of porous structure with complex internal and external structures for bone tissue engineering applications. To optimize the 3DP manufacturing process and to produce 3D printed parts with the requisite architecture and strength, there was a need to fine-tune the printing parameters. The purpose of this study was to develop optimal processing parameters based on a design of the experiments approach to evaluate the ability of 3DP for making calcium sulfate-based scaffold prototypes. The major printing parameters examined in this study were layer thickness, delay time of spreading the next layer, and build orientation of the specimens. Scaffold dimensional accuracy, porosity, and mechanical stiffness were systematically investigated using a design of experiment approach. Resulting macro-porous structures were also studied to evaluate the potential of 3DP technology for meeting the small-scale geometric requirements of bone scaffolds. Signal-to-noise ratio and analysis of variance (ANOVA) were employed to identify the important factors that influence optimal 3D printed part characteristics. The results showed that samples built using the minimum layer thickness (89 μm) and x-direction of build bed with 300 ms delay time between spreading each layer yielded the highest quality scaffold prototypes; thus, these parameters are suggested for fabrication of an engineered bone tissue scaffold. Furthermore, this study identified orientation and new layer spreading delay time as the most important factors influencing the dimensional accuracy, compressive strength, and porosity of the samples. Elsevier 2016 Article PeerReviewed Asadi-Eydivand, M. and Solati-Hashjin, M. and Farzad, A. and Abu Osman, Noor Azuan (2016) Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes. Robotics and Computer-Integrated Manufacturing, 37. pp. 57-67. ISSN 0736-5845 https://doi.org/10.1016/j.rcim.2015.06.005 doi:10.1016/j.rcim.2015.06.005
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	R Medicine TA Engineering (General). Civil engineering (General)
spellingShingle	R Medicine TA Engineering (General). Civil engineering (General) Asadi-Eydivand, M. Solati-Hashjin, M. Farzad, A. Abu Osman, Noor Azuan Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
description	Abstract Additive manufacturing methods such as three-dimensional printing (3DP) show a great potential for production of porous structure with complex internal and external structures for bone tissue engineering applications. To optimize the 3DP manufacturing process and to produce 3D printed parts with the requisite architecture and strength, there was a need to fine-tune the printing parameters. The purpose of this study was to develop optimal processing parameters based on a design of the experiments approach to evaluate the ability of 3DP for making calcium sulfate-based scaffold prototypes. The major printing parameters examined in this study were layer thickness, delay time of spreading the next layer, and build orientation of the specimens. Scaffold dimensional accuracy, porosity, and mechanical stiffness were systematically investigated using a design of experiment approach. Resulting macro-porous structures were also studied to evaluate the potential of 3DP technology for meeting the small-scale geometric requirements of bone scaffolds. Signal-to-noise ratio and analysis of variance (ANOVA) were employed to identify the important factors that influence optimal 3D printed part characteristics. The results showed that samples built using the minimum layer thickness (89 μm) and x-direction of build bed with 300 ms delay time between spreading each layer yielded the highest quality scaffold prototypes; thus, these parameters are suggested for fabrication of an engineered bone tissue scaffold. Furthermore, this study identified orientation and new layer spreading delay time as the most important factors influencing the dimensional accuracy, compressive strength, and porosity of the samples.
format	Article
author	Asadi-Eydivand, M. Solati-Hashjin, M. Farzad, A. Abu Osman, Noor Azuan
author_facet	Asadi-Eydivand, M. Solati-Hashjin, M. Farzad, A. Abu Osman, Noor Azuan
author_sort	Asadi-Eydivand, M.
title	Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
title_short	Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
title_full	Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
title_fullStr	Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
title_full_unstemmed	Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes
title_sort	effect of technical parameters on porous structure and strength of 3d printed calcium sulfate prototypes
publisher	Elsevier
publishDate	2016
url	http://eprints.um.edu.my/18342/ https://doi.org/10.1016/j.rcim.2015.06.005
_version_	1643690678492856320
score	13.211869

Effect of technical parameters on porous structure and strength of 3D printed calcium sulfate prototypes

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