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Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia

We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase...

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Main Authors: Zan, H.A.M., Ponnampalavanar, S., Omar, S.F.S., Savithiri, P.D., Lim, Y.A.L., Tay, S.T.
Format: Article
Published: Malaysian Society for Parasitology 2016
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/18313/
https://drive.google.com/file/d/0B75lcx0mfp2OZGdoYW1qV2syaGc/view
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spelling my.um.eprints.183132017-11-17T07:38:19Z http://eprints.um.edu.my/18313/ Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia Zan, H.A.M. Ponnampalavanar, S. Omar, S.F.S. Savithiri, P.D. Lim, Y.A.L. Tay, S.T. R Medicine We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase chain reaction assay. The circulation of different genetic variants of O. tsutsugamushi strains might complicate the presentation and severity of scrub typhus. Loop-PCR is a promising diagnostic tool for rapid diagnosis of scrub typhus. Malaysian Society for Parasitology 2016 Article PeerReviewed Zan, H.A.M. and Ponnampalavanar, S. and Omar, S.F.S. and Savithiri, P.D. and Lim, Y.A.L. and Tay, S.T. (2016) Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia. Tropical Biomedicine, 33 (1). pp. 203-208. ISSN 0127-5720 https://drive.google.com/file/d/0B75lcx0mfp2OZGdoYW1qV2syaGc/view
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Zan, H.A.M.
Ponnampalavanar, S.
Omar, S.F.S.
Savithiri, P.D.
Lim, Y.A.L.
Tay, S.T.
Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
description We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase chain reaction assay. The circulation of different genetic variants of O. tsutsugamushi strains might complicate the presentation and severity of scrub typhus. Loop-PCR is a promising diagnostic tool for rapid diagnosis of scrub typhus.
format Article
author Zan, H.A.M.
Ponnampalavanar, S.
Omar, S.F.S.
Savithiri, P.D.
Lim, Y.A.L.
Tay, S.T.
author_facet Zan, H.A.M.
Ponnampalavanar, S.
Omar, S.F.S.
Savithiri, P.D.
Lim, Y.A.L.
Tay, S.T.
author_sort Zan, H.A.M.
title Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
title_short Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
title_full Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
title_fullStr Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
title_full_unstemmed Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia
title_sort genetic variants of orientia tsutsugamushi identified from scrub typhus cases in malaysia
publisher Malaysian Society for Parasitology
publishDate 2016
url http://eprints.um.edu.my/18313/
https://drive.google.com/file/d/0B75lcx0mfp2OZGdoYW1qV2syaGc/view
_version_ 1643690671128707072
score 13.211869

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