Cardiovascular risk scores do not account for the effect of treatment: a review.

The use of risk-factor-modifying drugs-for example, statins-and disease-modifying medication-for example, platelet inhibitors-was not accounted for. In addition, none of the risk scores addressed the effect of treatment drop-ins-that is, treatment started during the study period. Ideally, a risk sco...

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Main Authors: Liew, S.M., Doust, J., Glasziou, P.
Format: Article
Published: 2011
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Online Access:http://eprints.um.edu.my/1826/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072200/
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spelling my.um.eprints.18262011-07-23T01:43:33Z http://eprints.um.edu.my/1826/ Cardiovascular risk scores do not account for the effect of treatment: a review. Liew, S.M. Doust, J. Glasziou, P. R Medicine The use of risk-factor-modifying drugs-for example, statins-and disease-modifying medication-for example, platelet inhibitors-was not accounted for. In addition, none of the risk scores addressed the effect of treatment drop-ins-that is, treatment started during the study period. Ideally, a risk score should be derived from a population free from treatment. The lack of accounting for treatment effect and the wide variation in study characteristics, predictors and outcomes causes difficulties in the use of cardiovascular risk scores for clinical treatment decision. 2011-05 Article PeerReviewed Liew, S.M. and Doust, J. and Glasziou, P. (2011) Cardiovascular risk scores do not account for the effect of treatment: a review. Heart (British Cardiac Society), 97 (9). pp. 689-97. ISSN 1468-201X http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072200/ 21474616
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Liew, S.M.
Doust, J.
Glasziou, P.
Cardiovascular risk scores do not account for the effect of treatment: a review.
description The use of risk-factor-modifying drugs-for example, statins-and disease-modifying medication-for example, platelet inhibitors-was not accounted for. In addition, none of the risk scores addressed the effect of treatment drop-ins-that is, treatment started during the study period. Ideally, a risk score should be derived from a population free from treatment. The lack of accounting for treatment effect and the wide variation in study characteristics, predictors and outcomes causes difficulties in the use of cardiovascular risk scores for clinical treatment decision.
format Article
author Liew, S.M.
Doust, J.
Glasziou, P.
author_facet Liew, S.M.
Doust, J.
Glasziou, P.
author_sort Liew, S.M.
title Cardiovascular risk scores do not account for the effect of treatment: a review.
title_short Cardiovascular risk scores do not account for the effect of treatment: a review.
title_full Cardiovascular risk scores do not account for the effect of treatment: a review.
title_fullStr Cardiovascular risk scores do not account for the effect of treatment: a review.
title_full_unstemmed Cardiovascular risk scores do not account for the effect of treatment: a review.
title_sort cardiovascular risk scores do not account for the effect of treatment: a review.
publishDate 2011
url http://eprints.um.edu.my/1826/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072200/
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