Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis
Purpose: This study aims to determine if continuous infusion (CI) is associated with better clinical and pharmacokinetic/pharmacodynamic (PK/PD) outcomes compared to intermittent bolus (IB) dosing in critically ill patients with severe sepsis. Methods: This was a two-centre randomised controlled tri...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Springer Verlag (Germany)
2016
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/17981/ http://dx.doi.org/10.1007/s00134-015-4188-0 |
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