Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection
In this work, the composites of polyaniline/nano-hematite (α-Fe2O3)/Prussian Blue (PB) were successfully synthesized via a sonochemical method. This nanocomposite (PB/CPANI) has been used for the modification of paper-based sensors for cholesterol detection. The electrochemical studies of this nanoc...
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Royal Society of Chemistry
2016
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my.um.eprints.177162017-08-24T09:23:16Z http://eprints.um.edu.my/17716/ Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection Maluin, F.N. Mohamad, S. Rattanarat, P. Siangproh, W. Chailapakul, O. Issam, A.M. Manan, N.S.A. QD Chemistry In this work, the composites of polyaniline/nano-hematite (α-Fe2O3)/Prussian Blue (PB) were successfully synthesized via a sonochemical method. This nanocomposite (PB/CPANI) has been used for the modification of paper-based sensors for cholesterol detection. The electrochemical studies of this nanocomposite showed a well-defined cyclic voltammogram for hydrogen peroxide (H2O2) with a remarkable electrochemical sensitivity. This nanocomposite modified paper-based electrode also showed excellent electrocatalytic activity towards H2O2 in the interference-free cathodic region. In addition, cholesterol oxidase was immobilized on the PB/CPANI-modified paper-based electrode for selective detection of cholesterol. Under optimum conditions, a linear range of 0.6–6.0 mM with a very low detection limit of 0.52 mM for cholesterol and a good sensitivity of 411.7 μA mM−1 cm−2 were obtained which indicated that the method presented is outstandingly appropriate to determine cholesterol in bovine serum albumin. This work might be an alternative, interference-free, and cost-effective approach for biomonitoring of cholesterol both in methodological studies and in clinical laboratories. Royal Society of Chemistry 2016 Article PeerReviewed Maluin, F.N. and Mohamad, S. and Rattanarat, P. and Siangproh, W. and Chailapakul, O. and Issam, A.M. and Manan, N.S.A. (2016) Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection. Analytical Methods, 8 (45). pp. 8049-8058. ISSN 1759-9660 http://dx.doi.org/10.1039/C6AY02478E doi:10.1039/C6AY02478E |
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QD Chemistry Maluin, F.N. Mohamad, S. Rattanarat, P. Siangproh, W. Chailapakul, O. Issam, A.M. Manan, N.S.A. Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| description |
In this work, the composites of polyaniline/nano-hematite (α-Fe2O3)/Prussian Blue (PB) were successfully synthesized via a sonochemical method. This nanocomposite (PB/CPANI) has been used for the modification of paper-based sensors for cholesterol detection. The electrochemical studies of this nanocomposite showed a well-defined cyclic voltammogram for hydrogen peroxide (H2O2) with a remarkable electrochemical sensitivity. This nanocomposite modified paper-based electrode also showed excellent electrocatalytic activity towards H2O2 in the interference-free cathodic region. In addition, cholesterol oxidase was immobilized on the PB/CPANI-modified paper-based electrode for selective detection of cholesterol. Under optimum conditions, a linear range of 0.6–6.0 mM with a very low detection limit of 0.52 mM for cholesterol and a good sensitivity of 411.7 μA mM−1 cm−2 were obtained which indicated that the method presented is outstandingly appropriate to determine cholesterol in bovine serum albumin. This work might be an alternative, interference-free, and cost-effective approach for biomonitoring of cholesterol both in methodological studies and in clinical laboratories. |
| format |
Article |
| author |
Maluin, F.N. Mohamad, S. Rattanarat, P. Siangproh, W. Chailapakul, O. Issam, A.M. Manan, N.S.A. |
| author_facet |
Maluin, F.N. Mohamad, S. Rattanarat, P. Siangproh, W. Chailapakul, O. Issam, A.M. Manan, N.S.A. |
| author_sort |
Maluin, F.N. |
| title |
Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| title_short |
Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| title_full |
Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| title_fullStr |
Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| title_full_unstemmed |
Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| title_sort |
synthesis of pani/hematite/pb hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection |
| publisher |
Royal Society of Chemistry |
| publishDate |
2016 |
| url |
http://eprints.um.edu.my/17716/ http://dx.doi.org/10.1039/C6AY02478E |
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13.244404 |