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Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters

Purpose: To evaluate the effect of nocturnal intermittent peritoneal dialysis (NIPD) on intraocular pressure (IOP) and anterior segment optical coherence tomography (ASOCT) parameters. Systemic changes associated with NIPD were also analyzed. Methods: Observational study. Nonglaucomatous patients on...

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Main Authors: Chong, K.L., Samsudin, A., Keng, T.C., Kamalden, T.A., Ramli, N.
Format: Article
Published: Lippincott, Williams & Wilkins 2016
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/17674/
http://dx.doi.org/10.1097/IJG.0000000000000542
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spelling my.um.eprints.176742017-08-10T09:14:17Z http://eprints.um.edu.my/17674/ Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters Chong, K.L. Samsudin, A. Keng, T.C. Kamalden, T.A. Ramli, N. R Medicine Purpose: To evaluate the effect of nocturnal intermittent peritoneal dialysis (NIPD) on intraocular pressure (IOP) and anterior segment optical coherence tomography (ASOCT) parameters. Systemic changes associated with NIPD were also analyzed. Methods: Observational study. Nonglaucomatous patients on NIPD underwent systemic and ocular assessment including mean arterial pressure (MAP), body weight, serum osmolarity, visual acuity, IOP measurement, and ASOCT within 2 hours both before and after NIPD. The Zhongshan Angle Assessment Program (ZAAP) was used to measure ASOCT parameters including anterior chamber depth, anterior chamber width, anterior chamber area, anterior chamber volume, lens vault, angle opening distance, trabecular-iris space area, and angle recess area. T tests and Pearson correlation tests were performed with P<0.05 considered statistically significant. Results: A total of 46 eyes from 46 patients were included in the analysis. There were statistically significant reductions in IOP (-1.8±0.6 mm Hg, P=0.003), MAP (-11.9±3.1 mm Hg, P<0.001), body weight (-0.7±2.8 kg, P<0.001), and serum osmolarity (-3.4±2.0 mOsm/L, P=0.002) after NIPD. All the ASOCT parameters did not have any statistically significant changes after NIPD. There were no statistically significant correlations between the changes in IOP, MAP, body weight, and serum osmolarity (all P>0.05). Conclusions: NIPD results in reductions in IOP, MAP, body weight, and serum osmolarity in nonglaucomatous patients. Lippincott, Williams & Wilkins 2016 Article PeerReviewed Chong, K.L. and Samsudin, A. and Keng, T.C. and Kamalden, T.A. and Ramli, N. (2016) Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters. Journal of Glaucoma. p. 1. ISSN 1057-0829 http://dx.doi.org/10.1097/IJG.0000000000000542 doi:10.1097/IJG.0000000000000542
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Chong, K.L.
Samsudin, A.
Keng, T.C.
Kamalden, T.A.
Ramli, N.
Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
description Purpose: To evaluate the effect of nocturnal intermittent peritoneal dialysis (NIPD) on intraocular pressure (IOP) and anterior segment optical coherence tomography (ASOCT) parameters. Systemic changes associated with NIPD were also analyzed. Methods: Observational study. Nonglaucomatous patients on NIPD underwent systemic and ocular assessment including mean arterial pressure (MAP), body weight, serum osmolarity, visual acuity, IOP measurement, and ASOCT within 2 hours both before and after NIPD. The Zhongshan Angle Assessment Program (ZAAP) was used to measure ASOCT parameters including anterior chamber depth, anterior chamber width, anterior chamber area, anterior chamber volume, lens vault, angle opening distance, trabecular-iris space area, and angle recess area. T tests and Pearson correlation tests were performed with P<0.05 considered statistically significant. Results: A total of 46 eyes from 46 patients were included in the analysis. There were statistically significant reductions in IOP (-1.8±0.6 mm Hg, P=0.003), MAP (-11.9±3.1 mm Hg, P<0.001), body weight (-0.7±2.8 kg, P<0.001), and serum osmolarity (-3.4±2.0 mOsm/L, P=0.002) after NIPD. All the ASOCT parameters did not have any statistically significant changes after NIPD. There were no statistically significant correlations between the changes in IOP, MAP, body weight, and serum osmolarity (all P>0.05). Conclusions: NIPD results in reductions in IOP, MAP, body weight, and serum osmolarity in nonglaucomatous patients.
format Article
author Chong, K.L.
Samsudin, A.
Keng, T.C.
Kamalden, T.A.
Ramli, N.
author_facet Chong, K.L.
Samsudin, A.
Keng, T.C.
Kamalden, T.A.
Ramli, N.
author_sort Chong, K.L.
title Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
title_short Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
title_full Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
title_fullStr Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
title_full_unstemmed Effect of Nocturnal Intermittent Peritoneal Dialysis on Intraocular Pressure and Anterior Segment Optical Coherence Tomography Parameters
title_sort effect of nocturnal intermittent peritoneal dialysis on intraocular pressure and anterior segment optical coherence tomography parameters
publisher Lippincott, Williams & Wilkins
publishDate 2016
url http://eprints.um.edu.my/17674/
http://dx.doi.org/10.1097/IJG.0000000000000542
_version_ 1643690486557310976
score 13.211869

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