Inflammatory bowel disease: a survey of the epidemiology in Asia

Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studi...

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Main Authors: Goh, K.L., Xiao, S.-D.
Format: Article
Published: Blackwell Publishing 2009
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Online Access:http://eprints.um.edu.my/1676/
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-2980.2008.00355.x/abstract;jsessionid=73810B3BFCC2E79D86D292B8B8E01713.f04t03
http://dx.doi.org/10.1111/j.1751-2980.2008.00355.x
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spelling my.um.eprints.16762014-12-12T01:11:15Z http://eprints.um.edu.my/1676/ Inflammatory bowel disease: a survey of the epidemiology in Asia Goh, K.L. Xiao, S.-D. R Medicine Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an increase in the incidence of ulcerative colitis (UC) and a similar but lower rise in Crohn's disease (CD). The epidemiological changes that are taking place mirror that of the Western experience seen 50 years previously and seem to occur in parallel with the rapid socioeconomic development taking place in Asia. It appears that certain racial groups are more prone than others to develop IBD. For instance, Indians in South-East Asia have higher rates compared to Chinese and Malays. While there is host genetic predisposition, environmental factor(s) may be responsible for this difference. Migrant studies of South Asians in the UK, where second-generation immigrants have assumed incidence rates as high as the indigenous whites and Asian Jews who develop high incidence rates comparable to Jews from Europe or North America in Israel point to the role of environmental factors. It is unclear which specific factors are responsible. Studies have suggested a change in diet to a more Westernized one may underlie this epidemiological change in the Asian population. It is likely that there are racial groups amongst Asians who are more susceptible to IBD and who will demonstrate a higher frequency of IBD when exposed to putative environmental factors. Blackwell Publishing 2009-02 Article PeerReviewed Goh, K.L. and Xiao, S.-D. (2009) Inflammatory bowel disease: a survey of the epidemiology in Asia. Journal of Digestive Diseases, 10 (1). pp. 1-6. ISSN 1751-2980 http://onlinelibrary.wiley.com/doi/10.1111/j.1751-2980.2008.00355.x/abstract;jsessionid=73810B3BFCC2E79D86D292B8B8E01713.f04t03 http://dx.doi.org/10.1111/j.1751-2980.2008.00355.x
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Goh, K.L.
Xiao, S.-D.
Inflammatory bowel disease: a survey of the epidemiology in Asia
description Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an increase in the incidence of ulcerative colitis (UC) and a similar but lower rise in Crohn's disease (CD). The epidemiological changes that are taking place mirror that of the Western experience seen 50 years previously and seem to occur in parallel with the rapid socioeconomic development taking place in Asia. It appears that certain racial groups are more prone than others to develop IBD. For instance, Indians in South-East Asia have higher rates compared to Chinese and Malays. While there is host genetic predisposition, environmental factor(s) may be responsible for this difference. Migrant studies of South Asians in the UK, where second-generation immigrants have assumed incidence rates as high as the indigenous whites and Asian Jews who develop high incidence rates comparable to Jews from Europe or North America in Israel point to the role of environmental factors. It is unclear which specific factors are responsible. Studies have suggested a change in diet to a more Westernized one may underlie this epidemiological change in the Asian population. It is likely that there are racial groups amongst Asians who are more susceptible to IBD and who will demonstrate a higher frequency of IBD when exposed to putative environmental factors.
format Article
author Goh, K.L.
Xiao, S.-D.
author_facet Goh, K.L.
Xiao, S.-D.
author_sort Goh, K.L.
title Inflammatory bowel disease: a survey of the epidemiology in Asia
title_short Inflammatory bowel disease: a survey of the epidemiology in Asia
title_full Inflammatory bowel disease: a survey of the epidemiology in Asia
title_fullStr Inflammatory bowel disease: a survey of the epidemiology in Asia
title_full_unstemmed Inflammatory bowel disease: a survey of the epidemiology in Asia
title_sort inflammatory bowel disease: a survey of the epidemiology in asia
publisher Blackwell Publishing
publishDate 2009
url http://eprints.um.edu.my/1676/
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-2980.2008.00355.x/abstract;jsessionid=73810B3BFCC2E79D86D292B8B8E01713.f04t03
http://dx.doi.org/10.1111/j.1751-2980.2008.00355.x
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score 13.211869