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MycoCAP - Mycobacterium Comparative Analysis Platform

Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, e...

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Main Authors:	Choo, S.W., Ang, M.Y., Dutta, A., Tan, S.Y., Siow, C.C., Heydari, H., Mutha, N.V.R., Wee, W.Y., Wong, G.J.
Format:	Article
Published:	2015
Subjects:	Q Science (General) T Technology (General)
Online Access:	http://eprints.um.edu.my/16178/
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spelling	my.um.eprints.161782016-07-29T07:23:14Z http://eprints.um.edu.my/16178/ MycoCAP - Mycobacterium Comparative Analysis Platform Choo, S.W. Ang, M.Y. Dutta, A. Tan, S.Y. Siow, C.C. Heydari, H. Mutha, N.V.R. Wee, W.Y. Wong, G.J. Q Science (General) T Technology (General) Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp. With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my 2015 Article PeerReviewed Choo, S.W. and Ang, M.Y. and Dutta, A. and Tan, S.Y. and Siow, C.C. and Heydari, H. and Mutha, N.V.R. and Wee, W.Y. and Wong, G.J. (2015) MycoCAP - Mycobacterium Comparative Analysis Platform. Scientific Reports, 5. ISSN 2045-2322 DOI: 10.1038/srep18227
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	Q Science (General) T Technology (General)
spellingShingle	Q Science (General) T Technology (General) Choo, S.W. Ang, M.Y. Dutta, A. Tan, S.Y. Siow, C.C. Heydari, H. Mutha, N.V.R. Wee, W.Y. Wong, G.J. MycoCAP - Mycobacterium Comparative Analysis Platform
description	Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp. With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my
format	Article
author	Choo, S.W. Ang, M.Y. Dutta, A. Tan, S.Y. Siow, C.C. Heydari, H. Mutha, N.V.R. Wee, W.Y. Wong, G.J.
author_facet	Choo, S.W. Ang, M.Y. Dutta, A. Tan, S.Y. Siow, C.C. Heydari, H. Mutha, N.V.R. Wee, W.Y. Wong, G.J.
author_sort	Choo, S.W.
title	MycoCAP - Mycobacterium Comparative Analysis Platform
title_short	MycoCAP - Mycobacterium Comparative Analysis Platform
title_full	MycoCAP - Mycobacterium Comparative Analysis Platform
title_fullStr	MycoCAP - Mycobacterium Comparative Analysis Platform
title_full_unstemmed	MycoCAP - Mycobacterium Comparative Analysis Platform
title_sort	mycocap - mycobacterium comparative analysis platform
publishDate	2015
url	http://eprints.um.edu.my/16178/
_version_	1643690213504974848
score	13.211869

MycoCAP - Mycobacterium Comparative Analysis Platform

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