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An introduction to dengue-disease diagnostics

In this review, we discuss how dengue disease can be diagnosed accurately at the viremia phase and the fever phase. Diagnostic tools currently used to detect dengue virus (DENV) are virus isolation, capture IgM and IgG ELISA, real-time polymerase chain reaction (RT-PCR), and immunochromatography of...

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Main Authors: Darwish, Nadiya Taha, Alias, Y., Khor, S.M.
Format: Article
Language:English
Published: Elsevier 2015
Subjects:
Q Science (General)
QD Chemistry
Online Access:http://eprints.um.edu.my/15515/1/Trends_in_Analytical_Chemistry_67%282015%2945-55_%28post-print_version%29.pdf
http://eprints.um.edu.my/15515/
https://doi.org/10.1016/j.trac.2015.01.005
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spelling my.um.eprints.155152018-10-26T06:49:50Z http://eprints.um.edu.my/15515/ An introduction to dengue-disease diagnostics Darwish, Nadiya Taha Alias, Y. Khor, S.M. Q Science (General) QD Chemistry In this review, we discuss how dengue disease can be diagnosed accurately at the viremia phase and the fever phase. Diagnostic tools currently used to detect dengue virus (DENV) are virus isolation, capture IgM and IgG ELISA, real-time polymerase chain reaction (RT-PCR), and immunochromatography of the dengue NS1 antigen. First, we explain the advantages, the challenges and the limitations of different diagnostic tests. This account is followed by several examples using biosensors for detection of several important DENV biomarkers. Finally, we discuss our opinions regarding future perspectives in this field. Elsevier 2015 Article PeerReviewed application/pdf en http://eprints.um.edu.my/15515/1/Trends_in_Analytical_Chemistry_67%282015%2945-55_%28post-print_version%29.pdf Darwish, Nadiya Taha and Alias, Y. and Khor, S.M. (2015) An introduction to dengue-disease diagnostics. Trends in Analytical Chemistry, 67. pp. 45-55. ISSN 0165-9936 https://doi.org/10.1016/j.trac.2015.01.005 doi:10.1016/j.trac.2015.01.005
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Darwish, Nadiya Taha
Alias, Y.
Khor, S.M.
An introduction to dengue-disease diagnostics
description In this review, we discuss how dengue disease can be diagnosed accurately at the viremia phase and the fever phase. Diagnostic tools currently used to detect dengue virus (DENV) are virus isolation, capture IgM and IgG ELISA, real-time polymerase chain reaction (RT-PCR), and immunochromatography of the dengue NS1 antigen. First, we explain the advantages, the challenges and the limitations of different diagnostic tests. This account is followed by several examples using biosensors for detection of several important DENV biomarkers. Finally, we discuss our opinions regarding future perspectives in this field.
format Article
author Darwish, Nadiya Taha
Alias, Y.
Khor, S.M.
author_facet Darwish, Nadiya Taha
Alias, Y.
Khor, S.M.
author_sort Darwish, Nadiya Taha
title An introduction to dengue-disease diagnostics
title_short An introduction to dengue-disease diagnostics
title_full An introduction to dengue-disease diagnostics
title_fullStr An introduction to dengue-disease diagnostics
title_full_unstemmed An introduction to dengue-disease diagnostics
title_sort introduction to dengue-disease diagnostics
publisher Elsevier
publishDate 2015
url http://eprints.um.edu.my/15515/1/Trends_in_Analytical_Chemistry_67%282015%2945-55_%28post-print_version%29.pdf
http://eprints.um.edu.my/15515/
https://doi.org/10.1016/j.trac.2015.01.005
_version_ 1643690071698702336
score 13.211869

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