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An immunohistochemical study of the lining epithelium of odontogenic keratocyst.

The lining epithelium of 15 cases of odontogenic keratocyst (OKC) was evaluated immunohistochemically. The peroxidase-antiperoxidase technique was applied to study the distribution of polyclonal keratin and S-100 protein while the indirect method was used to examine monoclonal vimentin and desmin re...

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Main Authors: Siar, C.H., Ng, K.H.
Format: Article
Published: 1995
Subjects:
Oral surger
Online Access:http://eprints.um.edu.my/1476/
http://www.ncbi.nlm.nih.gov/pubmed/7490610
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spelling my.um.eprints.14762014-10-21T00:37:29Z http://eprints.um.edu.my/1476/ An immunohistochemical study of the lining epithelium of odontogenic keratocyst. Siar, C.H. Ng, K.H. Oral surger The lining epithelium of 15 cases of odontogenic keratocyst (OKC) was evaluated immunohistochemically. The peroxidase-antiperoxidase technique was applied to study the distribution of polyclonal keratin and S-100 protein while the indirect method was used to examine monoclonal vimentin and desmin reactivity. Consistent positive keratin staining was revealed in the lining epithelium of all 15 OKCs with additional intense staining in the stratum corneum. None of the cases showed vimentin or desmin reactivity within the lining epithelium elements. One of the 15 cysts studied showed positive S-100 protein staining in the nuclei of the lining epithelial cells. The pertinent literature on the immunophenotyping of the lining epithelium of OKC is reviewed. 1995-09 Article PeerReviewed Siar, C.H. and Ng, K.H. (1995) An immunohistochemical study of the lining epithelium of odontogenic keratocyst. The Journal of Nihon University School of Dentistry, 37 (3). pp. 163-9. ISSN 0029-0432 http://www.ncbi.nlm.nih.gov/pubmed/7490610 7490610
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Oral surger
spellingShingle Oral surger
Siar, C.H.
Ng, K.H.
An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
description The lining epithelium of 15 cases of odontogenic keratocyst (OKC) was evaluated immunohistochemically. The peroxidase-antiperoxidase technique was applied to study the distribution of polyclonal keratin and S-100 protein while the indirect method was used to examine monoclonal vimentin and desmin reactivity. Consistent positive keratin staining was revealed in the lining epithelium of all 15 OKCs with additional intense staining in the stratum corneum. None of the cases showed vimentin or desmin reactivity within the lining epithelium elements. One of the 15 cysts studied showed positive S-100 protein staining in the nuclei of the lining epithelial cells. The pertinent literature on the immunophenotyping of the lining epithelium of OKC is reviewed.
format Article
author Siar, C.H.
Ng, K.H.
author_facet Siar, C.H.
Ng, K.H.
author_sort Siar, C.H.
title An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
title_short An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
title_full An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
title_fullStr An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
title_full_unstemmed An immunohistochemical study of the lining epithelium of odontogenic keratocyst.
title_sort immunohistochemical study of the lining epithelium of odontogenic keratocyst.
publishDate 1995
url http://eprints.um.edu.my/1476/
http://www.ncbi.nlm.nih.gov/pubmed/7490610
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score 13.211869

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