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The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria

The aim of this study was to evaluate and compare the antibacterial effect of the commercially available mouth rinses containing 0.12% w/v chlorohexidine (CHX), 0.05% w/w cetylpiridinium chloride (CPC) and alcohol base mouthwash containing thymol (THY) towards mixed three common oral bacteria ,'...

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Main Author: Alias, F.
Format: Conference or Workshop Item
Language:English
Published: 2011
Subjects:
Q Science (General)
Online Access:http://eprints.um.edu.my/13454/1/The_comparison_of_the_antibacterial.pdf
http://eprints.um.edu.my/13454/
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spelling my.um.eprints.134542015-05-11T00:18:29Z http://eprints.um.edu.my/13454/ The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria Alias, F. Q Science (General) The aim of this study was to evaluate and compare the antibacterial effect of the commercially available mouth rinses containing 0.12% w/v chlorohexidine (CHX), 0.05% w/w cetylpiridinium chloride (CPC) and alcohol base mouthwash containing thymol (THY) towards mixed three common oral bacteria ,')'treptocoCClIS mutans, Streptococcus mitis and Streptococcus sanguis. The effect of these compounds will be used to suggest the mechanism of action of these mouth rinses as antibacterial agent in any mouth rinses product. Material and method: The mouth rinses were tested for sensitivity using Kirby-Bauer susceptibility test with principle of agar disc diffusion while broth micro-dilution assay was used to determine the minimal inhibition concentrations (MIC) and the minimal bactericidal concentration (MBC). Pure solution of 0.12% CHX was used as positive control and sterile deionised water was used as negative control. Results: Disc diffusion assay showed that the CHX and CPC are able to prevent the growth of the mixed oral bacteria at the tested concentrations. CHX significantly exhibited stronger antibacterial effect with inhibition zone (diameter mean: 2.73cm) compared to CPC Inhibition zone (diameter mean: 227cm). THY showed less susceptibility effect (resistant - no clear zone) when compared with blank control and positive control (diameter mean: 253). The MIC and MBC for CHX was 0003.75°0 w/v while for CPC 0.0125°'0 w/w This showed that CHX and CPC exhibited profound antibacterial activity on selected common oral bacteria as demonstrated by the very low MIC and MBC values. THY showed its antibacterial effect only at higher concentration (>50°-0 v/v). Conclusion: This implies that the Incorporation of CHX and (PC 111 mouth rinses are better than that containing THY 2011-05 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.um.edu.my/13454/1/The_comparison_of_the_antibacterial.pdf Alias, F. (2011) The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria. In: Seminar Kebangsaan Teknologi Makmal Ke-10, 29 May - 01 June 2011, Skudai, Johor Bahru.
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Alias, F.
The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
description The aim of this study was to evaluate and compare the antibacterial effect of the commercially available mouth rinses containing 0.12% w/v chlorohexidine (CHX), 0.05% w/w cetylpiridinium chloride (CPC) and alcohol base mouthwash containing thymol (THY) towards mixed three common oral bacteria ,')'treptocoCClIS mutans, Streptococcus mitis and Streptococcus sanguis. The effect of these compounds will be used to suggest the mechanism of action of these mouth rinses as antibacterial agent in any mouth rinses product. Material and method: The mouth rinses were tested for sensitivity using Kirby-Bauer susceptibility test with principle of agar disc diffusion while broth micro-dilution assay was used to determine the minimal inhibition concentrations (MIC) and the minimal bactericidal concentration (MBC). Pure solution of 0.12% CHX was used as positive control and sterile deionised water was used as negative control. Results: Disc diffusion assay showed that the CHX and CPC are able to prevent the growth of the mixed oral bacteria at the tested concentrations. CHX significantly exhibited stronger antibacterial effect with inhibition zone (diameter mean: 2.73cm) compared to CPC Inhibition zone (diameter mean: 227cm). THY showed less susceptibility effect (resistant - no clear zone) when compared with blank control and positive control (diameter mean: 253). The MIC and MBC for CHX was 0003.75°0 w/v while for CPC 0.0125°'0 w/w This showed that CHX and CPC exhibited profound antibacterial activity on selected common oral bacteria as demonstrated by the very low MIC and MBC values. THY showed its antibacterial effect only at higher concentration (>50°-0 v/v). Conclusion: This implies that the Incorporation of CHX and (PC 111 mouth rinses are better than that containing THY
format Conference or Workshop Item
author Alias, F.
author_facet Alias, F.
author_sort Alias, F.
title The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
title_short The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
title_full The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
title_fullStr The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
title_full_unstemmed The comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
title_sort comparison of the antibacterial effect of various mouth rinses towards common oral bacteria
publishDate 2011
url http://eprints.um.edu.my/13454/1/The_comparison_of_the_antibacterial.pdf
http://eprints.um.edu.my/13454/
_version_ 1643689554903826432
score 13.211869

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