Staff View: Bilateral pallidal stimulation for X-linked dystonia parkinsonism

Bilateral pallidal stimulation for X-linked dystonia parkinsonism

Objective: To report the clinical benefits of bilateral deep brain stimulation (DBS) of the globus pallidus internus (GPi) in a patient with X-linked dystonia parkinsonism (XDP). Design: Case report. Setting: Tertiary referral center. Patient: A 40-year-old Filipino man with genetically confirmed XD...

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Main Authors:	Wadia, Pettarusp M., Lim, Shen-Yang, Lozano, Andres M., Adams, John R., Poon, Yu-Yan, Diaz, Cristina Torres, Moro, Elena
Format:	Article
Published:	American Medical Association 2010
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/12605/ https://jamanetwork.com/journals/jamaneurology/fullarticle/1106588
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spelling	my.um.eprints.126052018-10-24T03:37:59Z http://eprints.um.edu.my/12605/ Bilateral pallidal stimulation for X-linked dystonia parkinsonism Wadia, Pettarusp M. Lim, Shen-Yang Lozano, Andres M. Adams, John R. Poon, Yu-Yan Diaz, Cristina Torres Moro, Elena R Medicine Objective: To report the clinical benefits of bilateral deep brain stimulation (DBS) of the globus pallidus internus (GPi) in a patient with X-linked dystonia parkinsonism (XDP). Design: Case report. Setting: Tertiary referral center. Patient: A 40-year-old Filipino man with genetically confirmed XDP and severely disabling generalized dystonia. Intervention: Bilateral GPi DBS. Main Outcome Measures: The primary outcome measures were the Burke-Fahn-Marsden Dystonia Scale (BFMDS) severity and disability scores, and the secondary outcome measure was the Unified Parkinson Disease Rating Scores. Results: At the 1-year postoperative follow-up, there was 80.4% improvement in the BFMDS severity score and 66.7% improvement in the BFMDS disability score. Conclusion: Bilateral GPi DBS seems to be very effective in improving dystonia in XDP. American Medical Association 2010 Article PeerReviewed Wadia, Pettarusp M. and Lim, Shen-Yang and Lozano, Andres M. and Adams, John R. and Poon, Yu-Yan and Diaz, Cristina Torres and Moro, Elena (2010) Bilateral pallidal stimulation for X-linked dystonia parkinsonism. Archives of Neurology, 67 (8). pp. 1012-1017. ISSN 0003-9942 https://jamanetwork.com/journals/jamaneurology/fullarticle/1106588 doi:10.1001/archneurol.2010.187
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	R Medicine
spellingShingle	R Medicine Wadia, Pettarusp M. Lim, Shen-Yang Lozano, Andres M. Adams, John R. Poon, Yu-Yan Diaz, Cristina Torres Moro, Elena Bilateral pallidal stimulation for X-linked dystonia parkinsonism
description	Objective: To report the clinical benefits of bilateral deep brain stimulation (DBS) of the globus pallidus internus (GPi) in a patient with X-linked dystonia parkinsonism (XDP). Design: Case report. Setting: Tertiary referral center. Patient: A 40-year-old Filipino man with genetically confirmed XDP and severely disabling generalized dystonia. Intervention: Bilateral GPi DBS. Main Outcome Measures: The primary outcome measures were the Burke-Fahn-Marsden Dystonia Scale (BFMDS) severity and disability scores, and the secondary outcome measure was the Unified Parkinson Disease Rating Scores. Results: At the 1-year postoperative follow-up, there was 80.4% improvement in the BFMDS severity score and 66.7% improvement in the BFMDS disability score. Conclusion: Bilateral GPi DBS seems to be very effective in improving dystonia in XDP.
format	Article
author	Wadia, Pettarusp M. Lim, Shen-Yang Lozano, Andres M. Adams, John R. Poon, Yu-Yan Diaz, Cristina Torres Moro, Elena
author_facet	Wadia, Pettarusp M. Lim, Shen-Yang Lozano, Andres M. Adams, John R. Poon, Yu-Yan Diaz, Cristina Torres Moro, Elena
author_sort	Wadia, Pettarusp M.
title	Bilateral pallidal stimulation for X-linked dystonia parkinsonism
title_short	Bilateral pallidal stimulation for X-linked dystonia parkinsonism
title_full	Bilateral pallidal stimulation for X-linked dystonia parkinsonism
title_fullStr	Bilateral pallidal stimulation for X-linked dystonia parkinsonism
title_full_unstemmed	Bilateral pallidal stimulation for X-linked dystonia parkinsonism
title_sort	bilateral pallidal stimulation for x-linked dystonia parkinsonism
publisher	American Medical Association
publishDate	2010
url	http://eprints.um.edu.my/12605/ https://jamanetwork.com/journals/jamaneurology/fullarticle/1106588
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score	13.211869

Bilateral pallidal stimulation for X-linked dystonia parkinsonism

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