Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius
Eucophylline (1), a new tetracyclic vinylquinoline alkaloid, was isolated from the bark of Leuconotis eugenifolius together with leucophyllidine (2). The structure and absolute configuration of 1 were elucidated on the basis of 2D NMR correlations and simulated CD analysis. Leucophyllidine (2) showe...
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2010
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my.um.eprints.122492019-03-01T08:51:35Z http://eprints.um.edu.my/12249/ Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius Deguchi, J. Shoji, T. Nugroho, A.E. Hirasawa, Y. Hosoya, T. Shirota, O. Awang, Khalijah Hadi, A.H.A. Morita, H. Q Science (General) Eucophylline (1), a new tetracyclic vinylquinoline alkaloid, was isolated from the bark of Leuconotis eugenifolius together with leucophyllidine (2). The structure and absolute configuration of 1 were elucidated on the basis of 2D NMR correlations and simulated CD analysis. Leucophyllidine (2) showed iNOS inhibitory activity and decreased the iNOS protein expression dose-dependently. American Chemical Society 2010 Article PeerReviewed Deguchi, J. and Shoji, T. and Nugroho, A.E. and Hirasawa, Y. and Hosoya, T. and Shirota, O. and Awang, Khalijah and Hadi, A.H.A. and Morita, H. (2010) Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius. Journal of Natural Products-Copublished with the Am. Soc. of Pharmacognosy, 73 (10). pp. 1727-1729. |
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Q Science (General) Deguchi, J. Shoji, T. Nugroho, A.E. Hirasawa, Y. Hosoya, T. Shirota, O. Awang, Khalijah Hadi, A.H.A. Morita, H. Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| description |
Eucophylline (1), a new tetracyclic vinylquinoline alkaloid, was isolated from the bark of Leuconotis eugenifolius together with leucophyllidine (2). The structure and absolute configuration of 1 were elucidated on the basis of 2D NMR correlations and simulated CD analysis. Leucophyllidine (2) showed iNOS inhibitory activity and decreased the iNOS protein expression dose-dependently. |
| format |
Article |
| author |
Deguchi, J. Shoji, T. Nugroho, A.E. Hirasawa, Y. Hosoya, T. Shirota, O. Awang, Khalijah Hadi, A.H.A. Morita, H. |
| author_facet |
Deguchi, J. Shoji, T. Nugroho, A.E. Hirasawa, Y. Hosoya, T. Shirota, O. Awang, Khalijah Hadi, A.H.A. Morita, H. |
| author_sort |
Deguchi, J. |
| title |
Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| title_short |
Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| title_full |
Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| title_fullStr |
Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| title_full_unstemmed |
Eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| title_sort |
eucophylline, a tetracyclic vinylquinoline alkaloid from leuconotis eugenifolius |
| publisher |
American Chemical Society |
| publishDate |
2010 |
| url |
http://eprints.um.edu.my/12249/ |
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1643689257378775040 |
| score |
13.211869 |