Progressive multifocal leukoencephalopathy limited to the posterior fossa
Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease caused by the reactivation of JC papova virus usually in immunocompromised hosts.(1) The disease is a chronic viral infection resulting in mortality within a year.(2) The condition characterized by white...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
2010
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/11919/ |
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| Summary: | Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease caused by the reactivation of JC papova virus usually in immunocompromised hosts.(1) The disease is a chronic viral infection resulting in mortality within a year.(2) The condition characterized by white matter changes in multiple locations of the brain is caused by destruction of the oligodendrogliocytes.(2) We report a case of AIDS associated PML presenting with progressive cerebellar symptoms, with the unusual feature of imaging abnormalities limited to the posterior fossa. |
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