Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine

Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine.

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Bibliographic Details
Main Authors: Kam, T.S., Ziegler, R.E., Tan, S.J., Porco Jr., J.A.
Format: Article
Language:English
Published: Wiley-VCH Verlag 2012
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Online Access:http://eprints.um.edu.my/10389/1/Development_of_an_Alkaloid.pdf
http://eprints.um.edu.my/10389/
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