Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia

Heart failure in many patients is due to left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. , This quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sect...

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Main Authors: Chia, Y.C., Ching, S.M., Wan Ahmad, W.A., Jalalian, M.
Format: Article
Language:English
Published: Marsland Press 2012
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Online Access:http://eprints.um.edu.my/10154/1/Prevalence_of_Left_Ventricular_Diastolic_Dysfunction_among_Hypertensive_Adults_in_Klang_Valley%2C_Malaysia.pdf
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spelling my.um.eprints.101542014-10-27T01:45:27Z http://eprints.um.edu.my/10154/ Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia Chia, Y.C. Ching, S.M. Wan Ahmad, W.A. Jalalian, M. R Medicine (General) Heart failure in many patients is due to left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. , This quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sectional study was conducted among 359 hypertensive patients who underwent echocardiography to define their cardiac structure and function. The peak ratio of early to late diastolic filling velocity was used to assess the LVDD. The Framingham Coronary Heart Disease risk score was derived from the most recent blood test available in the previous year. SPSS version 19 was used to analyze the data. Echocardiographic LVDD was found in 68% of the participants. Of the 243 hypertensive subjects who had LVDD, 69.5% did not have any left ventricular hypertrophy (LVH) while 30.5% had LVH. Age (odds ratio (OR) 1.11, 95% confidence interval (CI) 1.07-1.15), fasting blood glucose (OR 1.18, 95% CI 1.02-1.37), poor blood pressure control (OR 1.93, 95% CI 1.12-3.32), central obesity (OR 2.06, 95% CI 1.17-3.64), and LVH (OR 2.76, 95% CI 1.29- 5.90) were found to have a significant positive relation with LVDD. Poor hypertension control, diabetes, older age, central obesity, and LVH are the predictors for the development of diastolic dysfunction. Marsland Press 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10154/1/Prevalence_of_Left_Ventricular_Diastolic_Dysfunction_among_Hypertensive_Adults_in_Klang_Valley%2C_Malaysia.pdf Chia, Y.C. and Ching, S.M. and Wan Ahmad, W.A. and Jalalian, M. (2012) Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia. Life Science Journal, 9 (3). pp. 713-719. ISSN 1097-8135
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Chia, Y.C.
Ching, S.M.
Wan Ahmad, W.A.
Jalalian, M.
Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
description Heart failure in many patients is due to left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. , This quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sectional study was conducted among 359 hypertensive patients who underwent echocardiography to define their cardiac structure and function. The peak ratio of early to late diastolic filling velocity was used to assess the LVDD. The Framingham Coronary Heart Disease risk score was derived from the most recent blood test available in the previous year. SPSS version 19 was used to analyze the data. Echocardiographic LVDD was found in 68% of the participants. Of the 243 hypertensive subjects who had LVDD, 69.5% did not have any left ventricular hypertrophy (LVH) while 30.5% had LVH. Age (odds ratio (OR) 1.11, 95% confidence interval (CI) 1.07-1.15), fasting blood glucose (OR 1.18, 95% CI 1.02-1.37), poor blood pressure control (OR 1.93, 95% CI 1.12-3.32), central obesity (OR 2.06, 95% CI 1.17-3.64), and LVH (OR 2.76, 95% CI 1.29- 5.90) were found to have a significant positive relation with LVDD. Poor hypertension control, diabetes, older age, central obesity, and LVH are the predictors for the development of diastolic dysfunction.
format Article
author Chia, Y.C.
Ching, S.M.
Wan Ahmad, W.A.
Jalalian, M.
author_facet Chia, Y.C.
Ching, S.M.
Wan Ahmad, W.A.
Jalalian, M.
author_sort Chia, Y.C.
title Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_short Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_full Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_fullStr Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_full_unstemmed Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_sort prevalence of left ventricular diastolic dysfunction among hypertensive adults in klang valley, malaysia
publisher Marsland Press
publishDate 2012
url http://eprints.um.edu.my/10154/1/Prevalence_of_Left_Ventricular_Diastolic_Dysfunction_among_Hypertensive_Adults_in_Klang_Valley%2C_Malaysia.pdf
http://eprints.um.edu.my/10154/
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score 13.211869