Transforming growth factor-ß enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes

Transforming growth factor-ß (TGF-ß) is known to act as a tumour suppressor early in carcinogenesis, but then switches to a pro-metastatic factor in some late stage cancers. However, the actions of TGF-ß are context dependent, and it is currently unclear how TGF-ß influences the progression of human...

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Bibliographic Details
Main Authors: Paterson, I.C., Davies, M., Prime, S.S., Eveson, J.W., Price, N., Ganapathy, A., D’Mello, A.
Format: Article
Language:English
Published: Blackwell Publishing 2012
Subjects:
Online Access:http://eprints.um.edu.my/10107/1/Transforming_growth_factor-b_enhances_invasion_and_metastasis.pdf
http://eprints.um.edu.my/10107/
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