Staff View: Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh

Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh

Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-deoxygoniopypyrone (7), pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds...

Full description

Saved in:

Bibliographic Details
Main Author:	Leong, K.H.
Format:	Article
Language:	English
Published:	Springer Verlag (Germany) 2012
Subjects:	Q Science (General) QD Chemistry QH301 Biology QK Botany R Medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine
Online Access:	http://eprints.um.edu.my/10005/1/Cytotoxic_and_antioxidant_compounds_from_the_stem_bark_of_Goniothalamus_tapisoides_Mat_Salleh.pdf http://eprints.um.edu.my/10005/ http://www.mdpi.com/1420-3049/18/1/128
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.um.eprints.10005
record_format	eprints
spelling	my.um.eprints.100052018-07-31T04:25:42Z http://eprints.um.edu.my/10005/ Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh Leong, K.H. Q Science (General) QD Chemistry QH301 Biology QK Botany R Medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-deoxygoniopypyrone (7), pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds were identified by spectroscopic analysis and, for known compounds, by comparison with published data. Goniothalamin (6) exhibited mild cytotoxic activity towards a colon cancer cell line (HT-29), with an IC50value of 64.17 ± 5.60 µM. Goniomicin B (2) give the highest antioxidant activity in the DPPH assay among all compounds tested, with an IC50 of 0.207 µM. Springer Verlag (Germany) 2012-12-21 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10005/1/Cytotoxic_and_antioxidant_compounds_from_the_stem_bark_of_Goniothalamus_tapisoides_Mat_Salleh.pdf Leong, K.H. (2012) Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh. Molecules Online, 18 (1). pp. 128-139. http://www.mdpi.com/1420-3049/18/1/128 10.3390/molecules18010128
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
language	English
topic	Q Science (General) QD Chemistry QH301 Biology QK Botany R Medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine
spellingShingle	Q Science (General) QD Chemistry QH301 Biology QK Botany R Medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine Leong, K.H. Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
description	Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-deoxygoniopypyrone (7), pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds were identified by spectroscopic analysis and, for known compounds, by comparison with published data. Goniothalamin (6) exhibited mild cytotoxic activity towards a colon cancer cell line (HT-29), with an IC50value of 64.17 ± 5.60 µM. Goniomicin B (2) give the highest antioxidant activity in the DPPH assay among all compounds tested, with an IC50 of 0.207 µM.
format	Article
author	Leong, K.H.
author_facet	Leong, K.H.
author_sort	Leong, K.H.
title	Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
title_short	Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
title_full	Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
title_fullStr	Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
title_full_unstemmed	Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh
title_sort	cytotoxic and antioxidant compoundsfrom the stem bark of goniothalamus tapisoides mat salleh
publisher	Springer Verlag (Germany)
publishDate	2012
url	http://eprints.um.edu.my/10005/1/Cytotoxic_and_antioxidant_compounds_from_the_stem_bark_of_Goniothalamus_tapisoides_Mat_Salleh.pdf http://eprints.um.edu.my/10005/ http://www.mdpi.com/1420-3049/18/1/128
_version_	1643688682468671488
score	13.211869

Cytotoxic and antioxidant Compoundsfrom the stem bark of goniothalamus tapisoides Mat Salleh

Similar Items