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Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman

Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation variabl...

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Main Author: Abdul Rahman, Nor Suraida
Format: Thesis
Language:English
Published: 2007
Subjects:
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:https://ir.uitm.edu.my/id/eprint/99962/1/99962.PDF
https://ir.uitm.edu.my/id/eprint/99962/
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spelling my.uitm.ir.999622024-08-07T14:05:32Z https://ir.uitm.edu.my/id/eprint/99962/ Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman Abdul Rahman, Nor Suraida RM Therapeutics. Pharmacology RS Pharmacy and materia medica Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation variables of nanophase gel as pre­ nanoemulsion over nanoemulsion properties. Pre-nanoemulsion gel formulation was first developed by varying sucrose monoester, glycerol/water (8:2) and safflower oil composition to form cubical liquid crystalline system or nanophase gel. Then, an emulsion in mean nanometer droplet size was produced by the mixing of pre­ nanoemulsion gel with distilled water under gentle agitation. The effects of different mechanical energy on mean droplet size and stability of nanoemulsion were then determined with respect to the variation of sucrose monoester and safflower oil composition. Smaller droplet sizes of nanoemulsion were produced using stirrer while bigger droplet sizes were obtained using homogenizer. The main mechanism of this nanoemulsion breakdown using high energy emulsification method might be due to coalescence phenomenon. In addition, destabilization of nanoemulsion in long term process could be attributed to Ostwald ripening. 2007 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/99962/1/99962.PDF Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman. (2007) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Abdul Rahman, Nor Suraida
Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
description Nanoemulsions are a class of emulsions with fine droplet size in the range of 20-500nm. Nanoemulsions are not thermodynamically stable and because of that their characteristics depend on the preparation method. The aim of this study is to investigate the effect of formulation and preparation variables of nanophase gel as pre­ nanoemulsion over nanoemulsion properties. Pre-nanoemulsion gel formulation was first developed by varying sucrose monoester, glycerol/water (8:2) and safflower oil composition to form cubical liquid crystalline system or nanophase gel. Then, an emulsion in mean nanometer droplet size was produced by the mixing of pre­ nanoemulsion gel with distilled water under gentle agitation. The effects of different mechanical energy on mean droplet size and stability of nanoemulsion were then determined with respect to the variation of sucrose monoester and safflower oil composition. Smaller droplet sizes of nanoemulsion were produced using stirrer while bigger droplet sizes were obtained using homogenizer. The main mechanism of this nanoemulsion breakdown using high energy emulsification method might be due to coalescence phenomenon. In addition, destabilization of nanoemulsion in long term process could be attributed to Ostwald ripening.
format Thesis
author Abdul Rahman, Nor Suraida
author_facet Abdul Rahman, Nor Suraida
author_sort Abdul Rahman, Nor Suraida
title Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
title_short Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
title_full Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
title_fullStr Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
title_full_unstemmed Formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / Nor Suraida Abdul Rahman
title_sort formulation and evaluation of safflower oil nanoemulsion for cosmetic applications using sucrose monoester / nor suraida abdul rahman
publishDate 2007
url https://ir.uitm.edu.my/id/eprint/99962/1/99962.PDF
https://ir.uitm.edu.my/id/eprint/99962/
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score 13.211869

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