Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir

Cassia alata L. (Gelanggang besar), commonly known as “seven golden candlesticks” is a shrub belonging to the family Leguminosae. Medicinal values of all plant parts have been reported. C. alata is a well-known remedy for ringworm and other related parasitical skin diseases such as purities, eczema,...

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Main Author: Syed Abd Kadir, Syed Abdul Illah Alyahya
Format: Thesis
Language:English
Published: 2005
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Online Access:https://ir.uitm.edu.my/id/eprint/99207/1/99207.pdf
https://ir.uitm.edu.my/id/eprint/99207/
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spelling my.uitm.ir.992072024-12-16T08:08:58Z https://ir.uitm.edu.my/id/eprint/99207/ Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir Syed Abd Kadir, Syed Abdul Illah Alyahya Biology Bioactive compounds Cassia alata L. (Gelanggang besar), commonly known as “seven golden candlesticks” is a shrub belonging to the family Leguminosae. Medicinal values of all plant parts have been reported. C. alata is a well-known remedy for ringworm and other related parasitical skin diseases such as purities, eczema, itching and scabies. A chemical study was done on the constituents of the dried barks and flowers of C. alata. The crude extracts were obtained by soaking the plant parts in dichloromethane followed by methanol. Isolation work was carried out using extensive chromatographic procedures. Torachrysone and three anthraquinones, known as chrysophanol, physcion, and emodin, along with mixture of sterols were isolated from the barks. Meanwhile, aloe-emodin, and rhein were isolated from flowers. Structures of all compounds were established based on spectral studies using ultraviolet-visible spectroscopy, infrared spectroscopy, one and two dimensional nuclear magnetic resonance spectra, and mass spectrospcopy. In addition structure of torachrysone was also confirmed through crystallographic studies. The various plant parts that are leaf, bark, flower, and pod were also screened for potential biological activities. Bioassays conducted were antioxidant, radical scavenging (DDPH), total phenolic content (TPC), antimicrobial, and antimalaria assay. 2005 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/99207/1/99207.pdf Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir. (2005) Masters thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/99207.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Biology
Bioactive compounds
spellingShingle Biology
Bioactive compounds
Syed Abd Kadir, Syed Abdul Illah Alyahya
Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
description Cassia alata L. (Gelanggang besar), commonly known as “seven golden candlesticks” is a shrub belonging to the family Leguminosae. Medicinal values of all plant parts have been reported. C. alata is a well-known remedy for ringworm and other related parasitical skin diseases such as purities, eczema, itching and scabies. A chemical study was done on the constituents of the dried barks and flowers of C. alata. The crude extracts were obtained by soaking the plant parts in dichloromethane followed by methanol. Isolation work was carried out using extensive chromatographic procedures. Torachrysone and three anthraquinones, known as chrysophanol, physcion, and emodin, along with mixture of sterols were isolated from the barks. Meanwhile, aloe-emodin, and rhein were isolated from flowers. Structures of all compounds were established based on spectral studies using ultraviolet-visible spectroscopy, infrared spectroscopy, one and two dimensional nuclear magnetic resonance spectra, and mass spectrospcopy. In addition structure of torachrysone was also confirmed through crystallographic studies. The various plant parts that are leaf, bark, flower, and pod were also screened for potential biological activities. Bioassays conducted were antioxidant, radical scavenging (DDPH), total phenolic content (TPC), antimicrobial, and antimalaria assay.
format Thesis
author Syed Abd Kadir, Syed Abdul Illah Alyahya
author_facet Syed Abd Kadir, Syed Abdul Illah Alyahya
author_sort Syed Abd Kadir, Syed Abdul Illah Alyahya
title Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
title_short Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
title_full Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
title_fullStr Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
title_full_unstemmed Chemical constituents and biological activities of bark and flowers of Cassia alata / Syed Abdul Illah Alyahya Syed Abd Kadir
title_sort chemical constituents and biological activities of bark and flowers of cassia alata / syed abdul illah alyahya syed abd kadir
publishDate 2005
url https://ir.uitm.edu.my/id/eprint/99207/1/99207.pdf
https://ir.uitm.edu.my/id/eprint/99207/
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score 13.223943