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Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar

The aim of the research is to synthesis 3,4-dimethoxy-l 0-benzyloxystilbene. In order to accomplish it, three established reactions have been used. Protection of 2-iodophenol with benzyl bromide as a protecting agent was the first step. Then, conversion of the 3,4- dimethoxybenzaldehyde to 3,4-dimet...

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Main Author: Abdul Shatar, Hanisah Jan
Format: Thesis
Language:English
Published: 2006
Subjects:
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:https://ir.uitm.edu.my/id/eprint/99040/1/99040.PDF
https://ir.uitm.edu.my/id/eprint/99040/
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spelling my.uitm.ir.990402024-07-24T03:07:52Z https://ir.uitm.edu.my/id/eprint/99040/ Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar Abdul Shatar, Hanisah Jan RM Therapeutics. Pharmacology RS Pharmacy and materia medica The aim of the research is to synthesis 3,4-dimethoxy-l 0-benzyloxystilbene. In order to accomplish it, three established reactions have been used. Protection of 2-iodophenol with benzyl bromide as a protecting agent was the first step. Then, conversion of the 3,4- dimethoxybenzaldehyde to 3,4-dimethoxystyrene has been done via Wittig reaction. Finally. both compounds were coupled together in the presence of palladium chloride as a catalyst and methyl triphenylphospine iodide as a ligand through Heck reaction (0.8187 g; 73.9% yield). TLC, lH-NMR, UV, IR and melting point characterization were used for conformation the of the products. The stilbene, which is expected to be formed, was successfully synthesized. 2006 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/99040/1/99040.PDF Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar. (2006) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Abdul Shatar, Hanisah Jan
Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
description The aim of the research is to synthesis 3,4-dimethoxy-l 0-benzyloxystilbene. In order to accomplish it, three established reactions have been used. Protection of 2-iodophenol with benzyl bromide as a protecting agent was the first step. Then, conversion of the 3,4- dimethoxybenzaldehyde to 3,4-dimethoxystyrene has been done via Wittig reaction. Finally. both compounds were coupled together in the presence of palladium chloride as a catalyst and methyl triphenylphospine iodide as a ligand through Heck reaction (0.8187 g; 73.9% yield). TLC, lH-NMR, UV, IR and melting point characterization were used for conformation the of the products. The stilbene, which is expected to be formed, was successfully synthesized.
format Thesis
author Abdul Shatar, Hanisah Jan
author_facet Abdul Shatar, Hanisah Jan
author_sort Abdul Shatar, Hanisah Jan
title Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
title_short Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
title_full Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
title_fullStr Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
title_full_unstemmed Synthesis of 3,4-dimethoxy-10-benzyloxystilbene / Hanisah Jan Abdul Shatar
title_sort synthesis of 3,4-dimethoxy-10-benzyloxystilbene / hanisah jan abdul shatar
publishDate 2006
url https://ir.uitm.edu.my/id/eprint/99040/1/99040.PDF
https://ir.uitm.edu.my/id/eprint/99040/
_version_ 1806422135486283776
score 13.211869

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