Cover Image

Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan

Fluorescent chemosensor have significant role in medical, environmental and biological applications. Receptor and signaling unit are important aspect in designing fluorescent chemosensor to selectively recognize metal ions for practical applications. In this study a series of chemosensors were synth...

Full description

Saved in:
Bibliographic Details
Main Author: Mohd Adnan, Siti Nur Ain
Format: Thesis
Language:English
Published: 2019
Online Access:https://ir.uitm.edu.my/id/eprint/90391/1/90391.pdf
https://ir.uitm.edu.my/id/eprint/90391/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.90391
record_format eprints
spelling my.uitm.ir.903912024-07-30T23:32:38Z https://ir.uitm.edu.my/id/eprint/90391/ Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan Mohd Adnan, Siti Nur Ain Fluorescent chemosensor have significant role in medical, environmental and biological applications. Receptor and signaling unit are important aspect in designing fluorescent chemosensor to selectively recognize metal ions for practical applications. In this study a series of chemosensors were synthesized for metal ions which bears diethylenetriamine and benzenyl derivatives as the receptor and dimethyl-phenyl-amine as fluorescence signal. Eight synthesized unsymmetrical ligands were prepared by using Schiff base technique that involved condensation of primary amine (-NH2) with an aldehyde (HC=O) to produce azomethine group (RCH=NR). All ligands were fully characterized by Fourier Transform Infrared (FT-IR), Proton Nuclear Magnetic Resonance (1H-NMR) and elemental analysis (CHNS). All ligands shown the characteristic FT-IR peak for C=N at 1596-1639 cm-1 and the 1H-NMR signal for HC=N at 8.11-8.51 ppm confirmed the formation of Schiff base ligand. Sensing properties for six synthesized ligands N-(4-Dimethylamino-benzylidene)-N'-{2-[(3-nitro-benzylidene)-amino]-ethyl}-ethane-1,2-diamine (L1), N-(4-Dimethylamino-benzylidene)-N'-{2-[(4-nitro-benzylidene)-amino]-ethyl}-ethane-1,2-diamine (L2), 3-[(2-{2-[(4-Dimethylamino-benzylidene)-amino]-ethylamino}-ethylimino)-methyl]-phenol (L3), 4-[(2-{2-[(4-Dimethylamino-benzylidene)-amino]-ethylamino}-ethylimino)-methyl]-phenol (L4), N-(4-Dimethylamino-benzylidene)-N'-{2-[(pyridin-2-ylmethylene)-amino]-ethyl}-ethane-1,2-diamine (L5) and synthesis of N-(4-Dimethylamino-benzylidene)-N'-{2-[(pyridin-3-ylmethylene)-amino]-ethyl}-ethane-1,2-diamine (L6) were studied towards transition metal. The selectivity and sensitivity tests of ligands were conducted on several metal ions. The fluorescence measurements revealed that L5 was more selective towards Zn2+ while L1-L6 were selective towards Fe3+ ions and forms complexes in 1:1 ratio as evidenced by Job's plot analysis. The limit of detection for L5 was found to be 3.5 x 10-5 M and L1-L6 were 1.42 x 10-6 M, 3.76 x 10-6 M, 1.58 x 10-6 M, 5.37 x 10-6 M and 6.49 x 10-6 M respectively. These sensors also exhibit a very good fluorescence sensing ability towards Zn2+ and Fe3+ at pH 7.0. Therefore, this fluorescent sensor can be applied to monitor the presence of heavy metals both in environment and biology conditions. 2019 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/90391/1/90391.pdf Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan. (2019) Masters thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/90391.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
description Fluorescent chemosensor have significant role in medical, environmental and biological applications. Receptor and signaling unit are important aspect in designing fluorescent chemosensor to selectively recognize metal ions for practical applications. In this study a series of chemosensors were synthesized for metal ions which bears diethylenetriamine and benzenyl derivatives as the receptor and dimethyl-phenyl-amine as fluorescence signal. Eight synthesized unsymmetrical ligands were prepared by using Schiff base technique that involved condensation of primary amine (-NH2) with an aldehyde (HC=O) to produce azomethine group (RCH=NR). All ligands were fully characterized by Fourier Transform Infrared (FT-IR), Proton Nuclear Magnetic Resonance (1H-NMR) and elemental analysis (CHNS). All ligands shown the characteristic FT-IR peak for C=N at 1596-1639 cm-1 and the 1H-NMR signal for HC=N at 8.11-8.51 ppm confirmed the formation of Schiff base ligand. Sensing properties for six synthesized ligands N-(4-Dimethylamino-benzylidene)-N'-{2-[(3-nitro-benzylidene)-amino]-ethyl}-ethane-1,2-diamine (L1), N-(4-Dimethylamino-benzylidene)-N'-{2-[(4-nitro-benzylidene)-amino]-ethyl}-ethane-1,2-diamine (L2), 3-[(2-{2-[(4-Dimethylamino-benzylidene)-amino]-ethylamino}-ethylimino)-methyl]-phenol (L3), 4-[(2-{2-[(4-Dimethylamino-benzylidene)-amino]-ethylamino}-ethylimino)-methyl]-phenol (L4), N-(4-Dimethylamino-benzylidene)-N'-{2-[(pyridin-2-ylmethylene)-amino]-ethyl}-ethane-1,2-diamine (L5) and synthesis of N-(4-Dimethylamino-benzylidene)-N'-{2-[(pyridin-3-ylmethylene)-amino]-ethyl}-ethane-1,2-diamine (L6) were studied towards transition metal. The selectivity and sensitivity tests of ligands were conducted on several metal ions. The fluorescence measurements revealed that L5 was more selective towards Zn2+ while L1-L6 were selective towards Fe3+ ions and forms complexes in 1:1 ratio as evidenced by Job's plot analysis. The limit of detection for L5 was found to be 3.5 x 10-5 M and L1-L6 were 1.42 x 10-6 M, 3.76 x 10-6 M, 1.58 x 10-6 M, 5.37 x 10-6 M and 6.49 x 10-6 M respectively. These sensors also exhibit a very good fluorescence sensing ability towards Zn2+ and Fe3+ at pH 7.0. Therefore, this fluorescent sensor can be applied to monitor the presence of heavy metals both in environment and biology conditions.
format Thesis
author Mohd Adnan, Siti Nur Ain
spellingShingle Mohd Adnan, Siti Nur Ain
Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
author_facet Mohd Adnan, Siti Nur Ain
author_sort Mohd Adnan, Siti Nur Ain
title Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
title_short Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
title_full Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
title_fullStr Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
title_full_unstemmed Unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of Fe(III) and Zn(II) / Siti Nur Ain Mohd Adnan
title_sort unsymmetrical diethylenetriamine fluorescent chemosensors for selective recognition of fe(iii) and zn(ii) / siti nur ain mohd adnan
publishDate 2019
url https://ir.uitm.edu.my/id/eprint/90391/1/90391.pdf
https://ir.uitm.edu.my/id/eprint/90391/
_version_ 1806454654044733440
score 13.211869

Similar Items