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Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat

Plectranthus amboinicus has been used in folk medicine to treat asthma and relieve colds, headaches, and fevers. It is frequently used due to its inexpensive cost, ease of availability, and low risk of adverse effects. The leaves have been shown to be potentially used as a bronchodilator and anti-My...

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Main Author: Rahmat, Nur Aliah Aqilah
Format: Student Project
Language:English
Published: 2023
Subjects:
Biochemistry
Online Access:https://ir.uitm.edu.my/id/eprint/87723/1/87723.pdf
https://ir.uitm.edu.my/id/eprint/87723/
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spelling my.uitm.ir.877232023-12-15T07:13:19Z https://ir.uitm.edu.my/id/eprint/87723/ Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat Rahmat, Nur Aliah Aqilah Biochemistry Plectranthus amboinicus has been used in folk medicine to treat asthma and relieve colds, headaches, and fevers. It is frequently used due to its inexpensive cost, ease of availability, and low risk of adverse effects. The leaves have been shown to be potentially used as a bronchodilator and anti-Mycobacterium tuberculosis in guinea pigs. Other than that, P. amboinicus can be a possible antitussive drug since the presence of polyphenolic polysaccharide (PP) conjugates in Lythrum salicaria and Erigeron canadensis produces antitussive properties in treating cough. Therefore, this study aims to extract the polyphenolic polysaccharide conjugates from P. amboinicus using reflux, to determine the functional groups of polyphenolic polysaccharide conjugates of P. amboinicus using Fourier-transform infrared (FTIR) spectroscopy, and to evaluate the concentration of total phenolic content (TPC), total carbohydrates content (TCC), and protein content using the colorimetric analysis. In this study, the percentage yield of polyphenolic polysaccharide conjugates from P. amboinicus is 1.5 %. The FTIR spectrum showed the hydroxyl (O-H) groups for saccharides and phenolic, C=C for alkene groups in phenolic, C-O and C-OH for alcohol groups of the saccharide rings, and COO- ester groups for saccharides. The total phenolic content for P. amboinicus leaves extract is 44.66 mg GAE/g extract, the carbohydrate content observed is 13.9%, and the protein content obtained is 0.08 mg/ml. Based on these findings, P. amboinicus extract contains polyphenolic polysaccharide conjugates. Overall, this study is a preliminary study to develop P. amboinicus polyphenolic polysaccharide conjugates from P. amboinicus leaves as antitussive drugs. 2023-02 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/87723/1/87723.pdf Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat. (2023) [Student Project] (Submitted)
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Biochemistry
spellingShingle Biochemistry
Rahmat, Nur Aliah Aqilah
Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
description Plectranthus amboinicus has been used in folk medicine to treat asthma and relieve colds, headaches, and fevers. It is frequently used due to its inexpensive cost, ease of availability, and low risk of adverse effects. The leaves have been shown to be potentially used as a bronchodilator and anti-Mycobacterium tuberculosis in guinea pigs. Other than that, P. amboinicus can be a possible antitussive drug since the presence of polyphenolic polysaccharide (PP) conjugates in Lythrum salicaria and Erigeron canadensis produces antitussive properties in treating cough. Therefore, this study aims to extract the polyphenolic polysaccharide conjugates from P. amboinicus using reflux, to determine the functional groups of polyphenolic polysaccharide conjugates of P. amboinicus using Fourier-transform infrared (FTIR) spectroscopy, and to evaluate the concentration of total phenolic content (TPC), total carbohydrates content (TCC), and protein content using the colorimetric analysis. In this study, the percentage yield of polyphenolic polysaccharide conjugates from P. amboinicus is 1.5 %. The FTIR spectrum showed the hydroxyl (O-H) groups for saccharides and phenolic, C=C for alkene groups in phenolic, C-O and C-OH for alcohol groups of the saccharide rings, and COO- ester groups for saccharides. The total phenolic content for P. amboinicus leaves extract is 44.66 mg GAE/g extract, the carbohydrate content observed is 13.9%, and the protein content obtained is 0.08 mg/ml. Based on these findings, P. amboinicus extract contains polyphenolic polysaccharide conjugates. Overall, this study is a preliminary study to develop P. amboinicus polyphenolic polysaccharide conjugates from P. amboinicus leaves as antitussive drugs.
format Student Project
author Rahmat, Nur Aliah Aqilah
author_facet Rahmat, Nur Aliah Aqilah
author_sort Rahmat, Nur Aliah Aqilah
title Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
title_short Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
title_full Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
title_fullStr Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
title_full_unstemmed Extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / Nur Aliah Aqilah Rahmat
title_sort extraction and characterization of polyphenolic polysaccharide conjugates from the leaves of plectranthus amboinicus / nur aliah aqilah rahmat
publishDate 2023
url https://ir.uitm.edu.my/id/eprint/87723/1/87723.pdf
https://ir.uitm.edu.my/id/eprint/87723/
_version_ 1787139547200487424
score 13.211869

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