In vitro evaluation of small molecules inhibitory activity against APOBEC3B cytosine deaminase enzyme / Maryan Mohamud Mohamed

Human APOBEC3B (A3B) is a member of the APOBEC3 (A3) family of cytidine deaminases, which function as DNA mutators and restrict viral pathogens and endogenous retrotransposons. APOBEC3B has both C-terminal catalytic (CTD) and N-terminal pseudo-catalytic (NTD) of zinc domains, only the CTD in APOBEC3...

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Bibliographic Details
Main Author: Mohamed, Maryan Mohamud
Format: Thesis
Language:English
Published: 2022
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/78077/1/78077.pdf
https://ir.uitm.edu.my/id/eprint/78077/
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