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Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]

Diabetes mellitus is a group of metabolic diseases which have several aetiologies that involve millions of people around the world. Hyperglycaemia, the hallmark of diabetes mellitus, causes detrimental complications such as nephropathy, neuropathy, retinopathy, and cardiovascular disease in both Typ...

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Main Authors: L.T., Younis, N.S., Razali, M.H., Zainal Abidin, M.I., Abu Hassan
Format: Article
Language:English
Published: Faculty of Dentistry, Universiti Teknologi MARA 2023
Subjects:
Diabetes Mellitus
Oral and dental medicine. Pathology. Diseases
Online Access:https://ir.uitm.edu.my/id/eprint/74502/1/74502.pdf
https://ir.uitm.edu.my/id/eprint/74502/
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id my.uitm.ir.74502
record_format eprints
spelling my.uitm.ir.745022023-09-04T15:14:49Z https://ir.uitm.edu.my/id/eprint/74502/ Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.] cos L.T., Younis N.S., Razali M.H., Zainal Abidin M.I., Abu Hassan Diabetes Mellitus Oral and dental medicine. Pathology. Diseases Diabetes mellitus is a group of metabolic diseases which have several aetiologies that involve millions of people around the world. Hyperglycaemia, the hallmark of diabetes mellitus, causes detrimental complications such as nephropathy, neuropathy, retinopathy, and cardiovascular disease in both Type 1 and 2 diabetic patients. Inflammaging is recently linked with the development of diabetic complications. Local cellular senescence and its senescence-associated secretory phenotype (SASP) are the main contributors to inflammaging which can be triggered and accelerated by high glucose level. Regarding the oral cavity, hyperglycaemia, provokes the severity of inflammation and destruction in the tooth supporting structures (periodontium) and increases the susceptibility to periodontitis and eventually tooth loss. This paper provides insights into the impact of hyperglycaemia in causing cellular senescence of teeth supporting tissues and escalating periodontal tissue deterioration. Faculty of Dentistry, Universiti Teknologi MARA 2023 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/74502/1/74502.pdf Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]. (2023) Compendium of Oral Science (CORALS) <https://ir.uitm.edu.my/view/publication/Compendium_of_Oral_Science_=28CORALS=29/>, 10 (1). pp. 1-11. ISSN 2489-1102; 2637-0611
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Diabetes Mellitus
Oral and dental medicine. Pathology. Diseases
spellingShingle Diabetes Mellitus
Oral and dental medicine. Pathology. Diseases
L.T., Younis
N.S., Razali
M.H., Zainal Abidin
M.I., Abu Hassan
Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
description Diabetes mellitus is a group of metabolic diseases which have several aetiologies that involve millions of people around the world. Hyperglycaemia, the hallmark of diabetes mellitus, causes detrimental complications such as nephropathy, neuropathy, retinopathy, and cardiovascular disease in both Type 1 and 2 diabetic patients. Inflammaging is recently linked with the development of diabetic complications. Local cellular senescence and its senescence-associated secretory phenotype (SASP) are the main contributors to inflammaging which can be triggered and accelerated by high glucose level. Regarding the oral cavity, hyperglycaemia, provokes the severity of inflammation and destruction in the tooth supporting structures (periodontium) and increases the susceptibility to periodontitis and eventually tooth loss. This paper provides insights into the impact of hyperglycaemia in causing cellular senescence of teeth supporting tissues and escalating periodontal tissue deterioration.
format Article
author L.T., Younis
N.S., Razali
M.H., Zainal Abidin
M.I., Abu Hassan
author_facet L.T., Younis
N.S., Razali
M.H., Zainal Abidin
M.I., Abu Hassan
author_sort L.T., Younis
title Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
title_short Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
title_full Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
title_fullStr Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
title_full_unstemmed Hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / Younis L.T. ... [et al.]
title_sort hyperglycaemia accelerates local cellular inflammaging senescence and alters the periodontal tissues environment during periodontitis / younis l.t. ... [et al.]
publisher Faculty of Dentistry, Universiti Teknologi MARA
publishDate 2023
url https://ir.uitm.edu.my/id/eprint/74502/1/74502.pdf
https://ir.uitm.edu.my/id/eprint/74502/
_version_ 1776250544041492480
score 13.211869

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