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Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali

Plants have always been used as traditional remedy in treating critical diseases. Free radical that causing diseases are scavenged by the antioxidant compound contains in plant. By using carbon dioxide (CO2) as the main solvent and ethanol as the co- solvent, the SFE operates at manipulated variable...

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Main Author: Mohd Razali, Nur Riana Anis
Format: Student Project
Language:English
Published: 2022
Subjects:
Chemical engineering
Special processes and operations
Extraction
Biotechnology
Plant biotechnology
Online Access:https://ir.uitm.edu.my/id/eprint/67388/1/67388.pdf
https://ir.uitm.edu.my/id/eprint/67388/
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spelling my.uitm.ir.673882022-10-28T03:42:30Z https://ir.uitm.edu.my/id/eprint/67388/ Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali Mohd Razali, Nur Riana Anis Chemical engineering Special processes and operations Extraction Biotechnology Plant biotechnology Plants have always been used as traditional remedy in treating critical diseases. Free radical that causing diseases are scavenged by the antioxidant compound contains in plant. By using carbon dioxide (CO2) as the main solvent and ethanol as the co- solvent, the SFE operates at manipulated variables. The Hibiscus rosa sinensis leaves are collected in Dungun, Terengganu and consequently cleaned, dried, grinded, and sieved. 15 grams of sample is used for each of the extraction on SFE machine. The temperature is manipulated at 40°C to 80°C. The optimum temperature was 50°C with extraction yield of 2.547%. The pressure is also varied is in a range of 150 bar to 350 bar which have optimum pressure of 300 bar with percentage yield of 2.553%. The difference sample particle size of 45 pm, 500 pm and 2000 pm is also studied to determine its effect on the percentage of yield extract. The optimum extraction yield was 2.767% at 45 pm. Radical scavenging activity of sample extracts were also determined based on the percent inhibition of DPPH which the highest percent is at 54.5% and concentration of 60 pg/ml. The half-maximal inhibitory concentration (IC50) is also calculated which Hibiscus rosa sinensis leaves has the IC50 of 58.54 pg/ml. It is concluded that the used of different extraction parameters of temperature, pressure, and particle size yield high amount of extract with a medium-active of antioxidant activity. 2022 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/67388/1/67388.pdf Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali. (2022) [Student Project] <http://terminalib.uitm.edu.my/67388.pdf> (Unpublished)
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Chemical engineering
Special processes and operations
Extraction
Biotechnology
Plant biotechnology
spellingShingle Chemical engineering
Special processes and operations
Extraction
Biotechnology
Plant biotechnology
Mohd Razali, Nur Riana Anis
Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
description Plants have always been used as traditional remedy in treating critical diseases. Free radical that causing diseases are scavenged by the antioxidant compound contains in plant. By using carbon dioxide (CO2) as the main solvent and ethanol as the co- solvent, the SFE operates at manipulated variables. The Hibiscus rosa sinensis leaves are collected in Dungun, Terengganu and consequently cleaned, dried, grinded, and sieved. 15 grams of sample is used for each of the extraction on SFE machine. The temperature is manipulated at 40°C to 80°C. The optimum temperature was 50°C with extraction yield of 2.547%. The pressure is also varied is in a range of 150 bar to 350 bar which have optimum pressure of 300 bar with percentage yield of 2.553%. The difference sample particle size of 45 pm, 500 pm and 2000 pm is also studied to determine its effect on the percentage of yield extract. The optimum extraction yield was 2.767% at 45 pm. Radical scavenging activity of sample extracts were also determined based on the percent inhibition of DPPH which the highest percent is at 54.5% and concentration of 60 pg/ml. The half-maximal inhibitory concentration (IC50) is also calculated which Hibiscus rosa sinensis leaves has the IC50 of 58.54 pg/ml. It is concluded that the used of different extraction parameters of temperature, pressure, and particle size yield high amount of extract with a medium-active of antioxidant activity.
format Student Project
author Mohd Razali, Nur Riana Anis
author_facet Mohd Razali, Nur Riana Anis
author_sort Mohd Razali, Nur Riana Anis
title Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
title_short Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
title_full Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
title_fullStr Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
title_full_unstemmed Effect of supercritical fluid extraction (SFE) parameters on antioxidant of hibiscus rosa sinensis leaves / Nur Riana Anis Mohd Razali
title_sort effect of supercritical fluid extraction (sfe) parameters on antioxidant of hibiscus rosa sinensis leaves / nur riana anis mohd razali
publishDate 2022
url https://ir.uitm.edu.my/id/eprint/67388/1/67388.pdf
https://ir.uitm.edu.my/id/eprint/67388/
_version_ 1748183973080596480
score 13.211869

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