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Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor

The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis...

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Main Author: Mohd Noor, Nurul Ain
Format: Thesis
Language:English
Published: 2012
Subjects:
Cell culture
Lasers
Online Access:https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf
https://ir.uitm.edu.my/id/eprint/66798/
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spelling my.uitm.ir.667982022-09-15T06:17:42Z https://ir.uitm.edu.my/id/eprint/66798/ Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor Mohd Noor, Nurul Ain Cell culture Lasers The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis were detected in both cells. For HCT-116, the aqueous extract of M. platytyrea induced apoptosis about 10 times higher than the control. Meanwhile, in MCF-7, apoptosis was induced about 47 times higher than the control using the same extract. This further suggested that the aqueous extract of M. platytyrea was more selective to induce apoptosis in breast cancer cells compared to colon cancer cells. 2012 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor. (2012) Degree thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/66798.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Cell culture
Lasers
spellingShingle Cell culture
Lasers
Mohd Noor, Nurul Ain
Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
description The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis were detected in both cells. For HCT-116, the aqueous extract of M. platytyrea induced apoptosis about 10 times higher than the control. Meanwhile, in MCF-7, apoptosis was induced about 47 times higher than the control using the same extract. This further suggested that the aqueous extract of M. platytyrea was more selective to induce apoptosis in breast cancer cells compared to colon cancer cells.
format Thesis
author Mohd Noor, Nurul Ain
author_facet Mohd Noor, Nurul Ain
author_sort Mohd Noor, Nurul Ain
title Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_short Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_full Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_fullStr Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_full_unstemmed Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_sort morphological changes during programmed cell death (pcd) using laser scanning confocal microscopy / nurul ain mohd noor
publishDate 2012
url https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf
https://ir.uitm.edu.my/id/eprint/66798/
_version_ 1744357296823074816
score 13.211869

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