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Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff

The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% o...

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Main Author: Yusoff, Noor Adilah
Format: Thesis
Language:English
Published: 2012
Subjects:
Drugs and their actions
Online Access:https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf
https://ir.uitm.edu.my/id/eprint/66705/
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spelling my.uitm.ir.667052022-09-14T03:20:43Z https://ir.uitm.edu.my/id/eprint/66705/ Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff Yusoff, Noor Adilah Drugs and their actions The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% of ethanol. The densities and the ultrasonic sound velocity datas obtained are duly treated so to find out the thermophysical parameters. The solubility data (presented elsewhere) are well correlated with the findings of the thermophysical parameters related to volumetric and acoustic studies. The most favourable environment as per the volumetric and acoustical analysis being characterized by a strong solute solvent interaction, open packing, less electrostriction, increased isentropic compressibility and decreased internal pressure. 2012 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff. (2012) Degree thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/66705.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Drugs and their actions
spellingShingle Drugs and their actions
Yusoff, Noor Adilah
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
description The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% of ethanol. The densities and the ultrasonic sound velocity datas obtained are duly treated so to find out the thermophysical parameters. The solubility data (presented elsewhere) are well correlated with the findings of the thermophysical parameters related to volumetric and acoustic studies. The most favourable environment as per the volumetric and acoustical analysis being characterized by a strong solute solvent interaction, open packing, less electrostriction, increased isentropic compressibility and decreased internal pressure.
format Thesis
author Yusoff, Noor Adilah
author_facet Yusoff, Noor Adilah
author_sort Yusoff, Noor Adilah
title Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
title_short Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
title_full Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
title_fullStr Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
title_full_unstemmed Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
title_sort combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / noor adilah yusoff
publishDate 2012
url https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf
https://ir.uitm.edu.my/id/eprint/66705/
_version_ 1744357292909789184
score 13.211869

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