Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]

Erythrina fusca Lour. (Family Fabaceae) is a flowering tree, locally known as ‘Chengkering’. The plant is traditionally used in the treatment of some symptoms related to bacterial infections such as skin itching and inflammations as well as on wounds. This work reports for the first time on the in v...

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Main Authors: Azmi, Adiez Sapura, Amini, Mohammad Humayoon, Syakir Nor Azman, Muhammad Farhan, Salim, Fatimah
Format: Article
Language:English
Published: Universiti Teknologi MARA 2022
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Online Access:https://ir.uitm.edu.my/id/eprint/58241/1/58241.pdf
https://ir.uitm.edu.my/id/eprint/58241/
https://scilett-fsg.uitm.edu.my/
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spelling my.uitm.ir.582412022-04-13T03:08:00Z https://ir.uitm.edu.my/id/eprint/58241/ Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.] Azmi, Adiez Sapura Amini, Mohammad Humayoon Syakir Nor Azman, Muhammad Farhan Salim, Fatimah Chemical engineering Erythrina fusca Lour. (Family Fabaceae) is a flowering tree, locally known as ‘Chengkering’. The plant is traditionally used in the treatment of some symptoms related to bacterial infections such as skin itching and inflammations as well as on wounds. This work reports for the first time on the in vitro antibacterial activity of methanolic leaf extract of E. fusca against some common bacterial strains such as Klebsiella pneumonia, Proteus vulgaris, Pseudomonas aeruginosa, Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus. The in vitro antibacterial assay was carried out using agar well diffusion method with the extract concentration of 3 mg/well and vancomycin 30 μg/well as the positive control. Except for K. pneumonia, it was found that the extract exhibits antibacterial effects against all the tested bacterial strains with the zone of inhibition (ZOI) in a range of 10.5 – 14 mm. Based on the preliminary phytochemical screening using standard qualitative phytochemical tests, the leaf extract contains a significant number of alkaloids, flavonoids, terpenoids, and tannins, which might contribute to its antibacterial activity. Both antibacterial properties and the presence of various phytochemicals in the extract could support the traditional uses of E. fusca in treating symptoms related to bacterial infections. The findings would serve as a basis for further exploration of the antibacterial potential of the plant’s leaves. Universiti Teknologi MARA 2022-01 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/58241/1/58241.pdf (2022) Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]. Science Letters (ScL), 16 (1): 12. pp. 60-71. ISSN (eISSN): 2682-8626 https://scilett-fsg.uitm.edu.my/
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Chemical engineering
spellingShingle Chemical engineering
Azmi, Adiez Sapura
Amini, Mohammad Humayoon
Syakir Nor Azman, Muhammad Farhan
Salim, Fatimah
Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
description Erythrina fusca Lour. (Family Fabaceae) is a flowering tree, locally known as ‘Chengkering’. The plant is traditionally used in the treatment of some symptoms related to bacterial infections such as skin itching and inflammations as well as on wounds. This work reports for the first time on the in vitro antibacterial activity of methanolic leaf extract of E. fusca against some common bacterial strains such as Klebsiella pneumonia, Proteus vulgaris, Pseudomonas aeruginosa, Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus. The in vitro antibacterial assay was carried out using agar well diffusion method with the extract concentration of 3 mg/well and vancomycin 30 μg/well as the positive control. Except for K. pneumonia, it was found that the extract exhibits antibacterial effects against all the tested bacterial strains with the zone of inhibition (ZOI) in a range of 10.5 – 14 mm. Based on the preliminary phytochemical screening using standard qualitative phytochemical tests, the leaf extract contains a significant number of alkaloids, flavonoids, terpenoids, and tannins, which might contribute to its antibacterial activity. Both antibacterial properties and the presence of various phytochemicals in the extract could support the traditional uses of E. fusca in treating symptoms related to bacterial infections. The findings would serve as a basis for further exploration of the antibacterial potential of the plant’s leaves.
format Article
author Azmi, Adiez Sapura
Amini, Mohammad Humayoon
Syakir Nor Azman, Muhammad Farhan
Salim, Fatimah
author_facet Azmi, Adiez Sapura
Amini, Mohammad Humayoon
Syakir Nor Azman, Muhammad Farhan
Salim, Fatimah
author_sort Azmi, Adiez Sapura
title Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
title_short Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
title_full Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
title_fullStr Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
title_full_unstemmed Antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / Adiez Sapura Azmi ... [et al.]
title_sort antibacterial activity and phytochemical screening of erythrina fusca lour. leaf extract (fabaceae) / adiez sapura azmi ... [et al.]
publisher Universiti Teknologi MARA
publishDate 2022
url https://ir.uitm.edu.my/id/eprint/58241/1/58241.pdf
https://ir.uitm.edu.my/id/eprint/58241/
https://scilett-fsg.uitm.edu.my/
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score 13.211869