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Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail

Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of ant...

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Bibliographic Details
Main Author: Ismail, Nur Liyana
Format: Thesis
Language:English
Published: 2017
Subjects:
Invertebrates
Individual drugs and other agents
Fruit and fruit culture
Online Access:https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf
https://ir.uitm.edu.my/id/eprint/50232/
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spelling my.uitm.ir.502322021-09-09T07:50:36Z https://ir.uitm.edu.my/id/eprint/50232/ Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail Ismail, Nur Liyana Invertebrates Individual drugs and other agents Fruit and fruit culture Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of anthelminthic activity and compared with the standard drug, Albendazole. In this study, the traditional method was used; boiling and evaporation method. Various concentrations of the extracts and Albendazole were tested at 60 mg/ml, 40 mg/ml and 20 mg/ml. Six earthworms were immersed in three concentrations of each extracts; papaya-pumpkin seeds and Albendazole. Confirmation of paralysis was reported when decreased in movement after shaken vigorously. Death was recorded after ascertaining that the worms neither moved when shaken vigorously nor dipped in warm water of 50oC. Results were expressed in terms of time for paralysis (P) and death time (D) of worms using mean SD and data analysis by One-way Anova. Interestingly, the time of death for worms showed that the crude aqueous extracts of seeds at concentration of 20 mg/ml could totally exterminate the worm at the shortest time (111.50 ± 4.95) compared to Albendazole (112.50 ± 4.96). In conclusion, the combination of Carica papaya and Cucurbita maxima is a good option to be taken as an alternative medicine in treating cases of intestinal worm infections. 2017 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf ID50232 Ismail, Nur Liyana (2017) Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail. Degree thesis, thesis, Universiti Teknologi Mara (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Invertebrates
Individual drugs and other agents
Fruit and fruit culture
spellingShingle Invertebrates
Individual drugs and other agents
Fruit and fruit culture
Ismail, Nur Liyana
Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
description Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of anthelminthic activity and compared with the standard drug, Albendazole. In this study, the traditional method was used; boiling and evaporation method. Various concentrations of the extracts and Albendazole were tested at 60 mg/ml, 40 mg/ml and 20 mg/ml. Six earthworms were immersed in three concentrations of each extracts; papaya-pumpkin seeds and Albendazole. Confirmation of paralysis was reported when decreased in movement after shaken vigorously. Death was recorded after ascertaining that the worms neither moved when shaken vigorously nor dipped in warm water of 50oC. Results were expressed in terms of time for paralysis (P) and death time (D) of worms using mean SD and data analysis by One-way Anova. Interestingly, the time of death for worms showed that the crude aqueous extracts of seeds at concentration of 20 mg/ml could totally exterminate the worm at the shortest time (111.50 ± 4.95) compared to Albendazole (112.50 ± 4.96). In conclusion, the combination of Carica papaya and Cucurbita maxima is a good option to be taken as an alternative medicine in treating cases of intestinal worm infections.
format Thesis
author Ismail, Nur Liyana
author_facet Ismail, Nur Liyana
author_sort Ismail, Nur Liyana
title Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_short Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_full Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_fullStr Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_full_unstemmed Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_sort investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / nur liyana ismail
publishDate 2017
url https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf
https://ir.uitm.edu.my/id/eprint/50232/
_version_ 1710678966767976448
score 13.211869

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