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Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar

Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ durati...

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Main Authors: Abdul Aziz, Mardiana Abdul Aziz, Omar, Effat Omar
Format: Article
Language:English
Published: Universiti Teknologi MARA Cawangan Selangor 2020
Subjects:
RB Pathology
Neoplasms. Tumors. Oncology
Online Access:http://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf
http://ir.uitm.edu.my/id/eprint/44193/
https://jchs-medicine.uitm.edu.my/index.php
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spelling my.uitm.ir.441932021-03-24T15:07:01Z http://ir.uitm.edu.my/id/eprint/44193/ Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar Abdul Aziz, Mardiana Abdul Aziz Omar, Effat Omar RB Pathology Neoplasms. Tumors. Oncology Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ duration which was clinically felt to be a pyogenic granuloma. Histopathological examination revealed a polypoid atypical vascular lesion with overlying peripheral epidermal collarette. Spindle cell proliferation typically seen in KS was also identified, which was positive for human herpesvirus 8 (HHV8) by immunohistochemistry, confirming the diagnosis of PGLKS. Upon review of the literature, our case is the 29th case of PGLKS reported to date, and only the sixth in Asian population. Particular attention to histomorphology, and demonstration of HHV8 in lesional tissue will aid accurate diagnosis of this rare entity. Universiti Teknologi MARA Cawangan Selangor 2020-11-01 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf Abdul Aziz, Mardiana Abdul Aziz and Omar, Effat Omar (2020) Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar. Journal of Clinical and Health Sciences, 5 (2). pp. 66-74. ISSN 0127 – 984X https://jchs-medicine.uitm.edu.my/index.php
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic RB Pathology
Neoplasms. Tumors. Oncology
spellingShingle RB Pathology
Neoplasms. Tumors. Oncology
Abdul Aziz, Mardiana Abdul Aziz
Omar, Effat Omar
Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
description Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ duration which was clinically felt to be a pyogenic granuloma. Histopathological examination revealed a polypoid atypical vascular lesion with overlying peripheral epidermal collarette. Spindle cell proliferation typically seen in KS was also identified, which was positive for human herpesvirus 8 (HHV8) by immunohistochemistry, confirming the diagnosis of PGLKS. Upon review of the literature, our case is the 29th case of PGLKS reported to date, and only the sixth in Asian population. Particular attention to histomorphology, and demonstration of HHV8 in lesional tissue will aid accurate diagnosis of this rare entity.
format Article
author Abdul Aziz, Mardiana Abdul Aziz
Omar, Effat Omar
author_facet Abdul Aziz, Mardiana Abdul Aziz
Omar, Effat Omar
author_sort Abdul Aziz, Mardiana Abdul Aziz
title Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
title_short Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
title_full Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
title_fullStr Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
title_full_unstemmed Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
title_sort pyogenic granuloma-like kaposi sarcoma: case report and review of literature / mardiana abdul aziz and effat omar
publisher Universiti Teknologi MARA Cawangan Selangor
publishDate 2020
url http://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf
http://ir.uitm.edu.my/id/eprint/44193/
https://jchs-medicine.uitm.edu.my/index.php
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score 13.211869

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