Staff View: Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]

Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]

The purpose of this study is to investigate the medicinal properties of Moringa oleifera (M. oleifera) leaves towards xanthine oxidase inhibitory activity by using water-based extraction methods such as boiling extraction, subcritical water extraction (SWE) and ultrasonic-assisted extraction (UAE)....

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Main Authors:	Mohamad Basri, Mohamad Daniel Mohamad Basri, Mad Nordin, Mariam Firdhaus, Mohamad Abdul Wahab, Izzati, Mohd Amir, Siti Nur Khairunisa, Mokhtar, Norrashidah
Format:	Article
Language:	English
Published:	Universiti Teknologi MARA 2020
Subjects:	Physical and theoretical chemistry Conditions and laws of chemical reactions Adsorption
Online Access:	http://ir.uitm.edu.my/id/eprint/42784/1/42784.pdf http://ir.uitm.edu.my/id/eprint/42784/
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spelling	my.uitm.ir.427842021-03-03T01:48:30Z http://ir.uitm.edu.my/id/eprint/42784/ Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.] Mohamad Basri, Mohamad Daniel Mohamad Basri Mad Nordin, Mariam Firdhaus Mohamad Abdul Wahab, Izzati Mohd Amir, Siti Nur Khairunisa Mokhtar, Norrashidah Physical and theoretical chemistry Conditions and laws of chemical reactions Adsorption The purpose of this study is to investigate the medicinal properties of Moringa oleifera (M. oleifera) leaves towards xanthine oxidase inhibitory activity by using water-based extraction methods such as boiling extraction, subcritical water extraction (SWE) and ultrasonic-assisted extraction (UAE). Boiling extraction is chosen as the control method in this study due to its commonly used in the industry. Water based extraction is investigated to determine if it can replace the conventional extraction method which uses organic solvent and time consuming. Temperature and time were investigated using central composite design (CCD) for maximum xanthine oxidase inhibitory activity in SWE and UAE. The boiling extraction is operated at fixed temperature of 100 °C while SWE is utilised at temperature of 100 to 180 °C and UAE at 30 to 60 °C with same time within 10 to 30 min. These variables are used to determine optimum condition on each method for xanthine oxidase inhibitory activity of M. oleifera leaves, then compared with the control method to identify ideal method of extraction. Thus, SWE (69.65 ± 0.1 %) at 180 °C and 20 min is the ideal method compared to UAE (48.89 ± 0.3 %) at 60 °C and 30 min and boiling extraction (41.88 ± 0.1 %) at 100 °C and 20 min due to higher percentage of xanthine oxidase inhibitory activity obtained on M. oleifera leaves. The findings of this study show that SWE offer better alternative for M. Oleifera extraction towards xanthine oxidase inhibitory compares to other methods. Universiti Teknologi MARA 2020 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/42784/1/42784.pdf Mohamad Basri, Mohamad Daniel Mohamad Basri and Mad Nordin, Mariam Firdhaus and Mohamad Abdul Wahab, Izzati and Mohd Amir, Siti Nur Khairunisa and Mokhtar, Norrashidah (2020) Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]. Malaysian Journal of Chemical Engineering and Technology (MJCET), 3 (1). pp. 50-55. ISSN 2682-8588
institution	Universiti Teknologi Mara
building	Tun Abdul Razak Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Mara
content_source	UiTM Institutional Repository
url_provider	http://ir.uitm.edu.my/
language	English
topic	Physical and theoretical chemistry Conditions and laws of chemical reactions Adsorption
spellingShingle	Physical and theoretical chemistry Conditions and laws of chemical reactions Adsorption Mohamad Basri, Mohamad Daniel Mohamad Basri Mad Nordin, Mariam Firdhaus Mohamad Abdul Wahab, Izzati Mohd Amir, Siti Nur Khairunisa Mokhtar, Norrashidah Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
description	The purpose of this study is to investigate the medicinal properties of Moringa oleifera (M. oleifera) leaves towards xanthine oxidase inhibitory activity by using water-based extraction methods such as boiling extraction, subcritical water extraction (SWE) and ultrasonic-assisted extraction (UAE). Boiling extraction is chosen as the control method in this study due to its commonly used in the industry. Water based extraction is investigated to determine if it can replace the conventional extraction method which uses organic solvent and time consuming. Temperature and time were investigated using central composite design (CCD) for maximum xanthine oxidase inhibitory activity in SWE and UAE. The boiling extraction is operated at fixed temperature of 100 °C while SWE is utilised at temperature of 100 to 180 °C and UAE at 30 to 60 °C with same time within 10 to 30 min. These variables are used to determine optimum condition on each method for xanthine oxidase inhibitory activity of M. oleifera leaves, then compared with the control method to identify ideal method of extraction. Thus, SWE (69.65 ± 0.1 %) at 180 °C and 20 min is the ideal method compared to UAE (48.89 ± 0.3 %) at 60 °C and 30 min and boiling extraction (41.88 ± 0.1 %) at 100 °C and 20 min due to higher percentage of xanthine oxidase inhibitory activity obtained on M. oleifera leaves. The findings of this study show that SWE offer better alternative for M. Oleifera extraction towards xanthine oxidase inhibitory compares to other methods.
format	Article
author	Mohamad Basri, Mohamad Daniel Mohamad Basri Mad Nordin, Mariam Firdhaus Mohamad Abdul Wahab, Izzati Mohd Amir, Siti Nur Khairunisa Mokhtar, Norrashidah
author_facet	Mohamad Basri, Mohamad Daniel Mohamad Basri Mad Nordin, Mariam Firdhaus Mohamad Abdul Wahab, Izzati Mohd Amir, Siti Nur Khairunisa Mokhtar, Norrashidah
author_sort	Mohamad Basri, Mohamad Daniel Mohamad Basri
title	Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
title_short	Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
title_full	Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
title_fullStr	Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
title_full_unstemmed	Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]
title_sort	water-based extraction methods of moringa oleifera leaves for xanthine oxidase inhibitory activity / mohamad daniel mohamad basri … [ et al.]
publisher	Universiti Teknologi MARA
publishDate	2020
url	http://ir.uitm.edu.my/id/eprint/42784/1/42784.pdf http://ir.uitm.edu.my/id/eprint/42784/
_version_	1693728913039032320
score	13.211869

Water-based extraction methods of Moringa oleifera leaves for xanthine oxidase inhibitory activity / Mohamad Daniel Mohamad Basri … [ et al.]

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