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Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir

AIM: To investigate prevalence and the risk factors of hospitalization resulting from antidiabetic related hypoglycemia in adult diabetic patients from 2010 to 2014 in Hospital Selayang. METHODS: This is a retrospective observational cohort study on 3770 adult hospitalized diabetic patients from the...

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Main Author: Mohd Hidzir, Sarina Anim
Format: Thesis
Language:English
Published: 2017
Subjects:
General special. Patient monitoring
Medical emergencies. Critical care. Intensive care. First aid
Online Access:http://ir.uitm.edu.my/id/eprint/26261/1/TM_SARINA%20ANIM%20MOHD%20HIDZIR%20PH%2017_5.pdf
http://ir.uitm.edu.my/id/eprint/26261/
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spelling my.uitm.ir.262612019-10-23T08:27:58Z http://ir.uitm.edu.my/id/eprint/26261/ Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir Mohd Hidzir, Sarina Anim General special. Patient monitoring Medical emergencies. Critical care. Intensive care. First aid AIM: To investigate prevalence and the risk factors of hospitalization resulting from antidiabetic related hypoglycemia in adult diabetic patients from 2010 to 2014 in Hospital Selayang. METHODS: This is a retrospective observational cohort study on 3770 adult hospitalized diabetic patients from the year 2010 to 2014 in Hospital Selayang. Medical records were reviewed for demographics, medical history, duration of diabetes, results of laboratory test and current diabetes therapy. Univariate analysis and multivariate logistic regression were used to determine risk factors of severe hypoglycemia. RESULTS: The overall prevalence for severe hypoglycaemia was 22%. Patient experiencing severe hypoglycaemia are more likely older, women, have lower HbA1c, have more concomitant medication and have renal impairment. More patients are also followed up at government clinics compared to government hospitals or non-government hospitals or clinic. Patients are mostly taking oral antidiabetic combinations of metformin and sulphonylureas (all p<0.05). Multiple logistic regression showed that the risk of severe hypoglycaemia increased with older age, lower Hba1C and impaired renal function. (all p < 0.05). CONCLUSION: Patients at risk for severe hypoglycaemia should have individualized diabetic treatment associated with less risk of hypoglycaemia and less stringent glycaemic targets. Patients at risk as well as family members or caregivers should also be given to education on the management of severe hypoglycaemia Keywords: severe hypoglycaemia, antidiabetic agents, oral hypoglycaemia, insulin therapy risk factors, Type 2 diabetes, Type 1 diabetes 2017 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/26261/1/TM_SARINA%20ANIM%20MOHD%20HIDZIR%20PH%2017_5.pdf Mohd Hidzir, Sarina Anim (2017) Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir. Masters thesis, Universiti Teknologi MARA.
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic General special. Patient monitoring
Medical emergencies. Critical care. Intensive care. First aid
spellingShingle General special. Patient monitoring
Medical emergencies. Critical care. Intensive care. First aid
Mohd Hidzir, Sarina Anim
Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
description AIM: To investigate prevalence and the risk factors of hospitalization resulting from antidiabetic related hypoglycemia in adult diabetic patients from 2010 to 2014 in Hospital Selayang. METHODS: This is a retrospective observational cohort study on 3770 adult hospitalized diabetic patients from the year 2010 to 2014 in Hospital Selayang. Medical records were reviewed for demographics, medical history, duration of diabetes, results of laboratory test and current diabetes therapy. Univariate analysis and multivariate logistic regression were used to determine risk factors of severe hypoglycemia. RESULTS: The overall prevalence for severe hypoglycaemia was 22%. Patient experiencing severe hypoglycaemia are more likely older, women, have lower HbA1c, have more concomitant medication and have renal impairment. More patients are also followed up at government clinics compared to government hospitals or non-government hospitals or clinic. Patients are mostly taking oral antidiabetic combinations of metformin and sulphonylureas (all p<0.05). Multiple logistic regression showed that the risk of severe hypoglycaemia increased with older age, lower Hba1C and impaired renal function. (all p < 0.05). CONCLUSION: Patients at risk for severe hypoglycaemia should have individualized diabetic treatment associated with less risk of hypoglycaemia and less stringent glycaemic targets. Patients at risk as well as family members or caregivers should also be given to education on the management of severe hypoglycaemia Keywords: severe hypoglycaemia, antidiabetic agents, oral hypoglycaemia, insulin therapy risk factors, Type 2 diabetes, Type 1 diabetes
format Thesis
author Mohd Hidzir, Sarina Anim
author_facet Mohd Hidzir, Sarina Anim
author_sort Mohd Hidzir, Sarina Anim
title Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
title_short Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
title_full Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
title_fullStr Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
title_full_unstemmed Hospitalization resulting from antidiabetic related hypoglycaemia / Sarina Anim Mohd Hidzir
title_sort hospitalization resulting from antidiabetic related hypoglycaemia / sarina anim mohd hidzir
publishDate 2017
url http://ir.uitm.edu.my/id/eprint/26261/1/TM_SARINA%20ANIM%20MOHD%20HIDZIR%20PH%2017_5.pdf
http://ir.uitm.edu.my/id/eprint/26261/
_version_ 1685650114481225728
score 13.211869

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