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The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman

Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study wa...

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Main Author: Osman, Nurain
Format: Thesis
Language:English
Published: 2015
Subjects:
Medical technology
Cancer
Diseases of the lungs
Radiography
Radiographic magnification
Online Access:http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf
http://ir.uitm.edu.my/id/eprint/22284/
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spelling my.uitm.ir.222842021-03-26T03:27:33Z http://ir.uitm.edu.my/id/eprint/22284/ The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman Osman, Nurain Medical technology Cancer Diseases of the lungs Radiography Radiographic magnification Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study was done at Diagnostic and Radiology Department, Selayang Hospital. The time frame for the sample data collection was taken from January 2013 until March 2015. 74 samples were selected based on the inclusion criteria of the study. The patient data selections were strictly the patients who underwent for both CT scan and MRI for detection of HCC. The reference of standard that was used to confirm the presence of the HCC included other interventional findings such as percutaneous biopsy, surgical resection and liver transplant. Result: The results were used in Bayers’ theorem to calculate the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of CT scan and MRI in detecting HCC. Based on the Bayers’ theorem, the sensitivity of CT scan and MRI is 81% and 94% respectively. The specificity of CT scan and MRI is 40% and 90% respectively. The positive predictive value of CT scan and MRI is 90% and 98% respectively. The negative predictive value of CT scan and MRI is 25% and 69% respectively. Diagnostic accuracy of CT scan and MRI in detecting HCC is 76% and 93% respectively. From the result, it showed that CT scan and MRI have higher sensitivity in detecting HCC. However, result was found MRI is more sensitive in detecting small HCC lesion less than 2 cm. Conclusion: CT scan and MRI show similar diagnostic performance for the detection of HCC. However, the advancement in MRI technologies and use of gadoxetix acidenhanced MRI improve the sensitivity in the detection of HCC lesion less than 2 cm in diameter. 2015 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf Osman, Nurain (2015) The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman. Degree thesis, Universiti Teknologi MARA, Selangor, Puncak Alam Campus.
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Medical technology
Cancer
Diseases of the lungs
Radiography
Radiographic magnification
spellingShingle Medical technology
Cancer
Diseases of the lungs
Radiography
Radiographic magnification
Osman, Nurain
The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
description Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study was done at Diagnostic and Radiology Department, Selayang Hospital. The time frame for the sample data collection was taken from January 2013 until March 2015. 74 samples were selected based on the inclusion criteria of the study. The patient data selections were strictly the patients who underwent for both CT scan and MRI for detection of HCC. The reference of standard that was used to confirm the presence of the HCC included other interventional findings such as percutaneous biopsy, surgical resection and liver transplant. Result: The results were used in Bayers’ theorem to calculate the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of CT scan and MRI in detecting HCC. Based on the Bayers’ theorem, the sensitivity of CT scan and MRI is 81% and 94% respectively. The specificity of CT scan and MRI is 40% and 90% respectively. The positive predictive value of CT scan and MRI is 90% and 98% respectively. The negative predictive value of CT scan and MRI is 25% and 69% respectively. Diagnostic accuracy of CT scan and MRI in detecting HCC is 76% and 93% respectively. From the result, it showed that CT scan and MRI have higher sensitivity in detecting HCC. However, result was found MRI is more sensitive in detecting small HCC lesion less than 2 cm. Conclusion: CT scan and MRI show similar diagnostic performance for the detection of HCC. However, the advancement in MRI technologies and use of gadoxetix acidenhanced MRI improve the sensitivity in the detection of HCC lesion less than 2 cm in diameter.
format Thesis
author Osman, Nurain
author_facet Osman, Nurain
author_sort Osman, Nurain
title The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_short The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_full The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_fullStr The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_full_unstemmed The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_sort efficacy of computed tomography (ct) scan and magnetic resonance imaging (mri) in detecting hepatocellular carcinoma (hcc) : retrospective study / nurain osman
publishDate 2015
url http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf
http://ir.uitm.edu.my/id/eprint/22284/
_version_ 1695534618561740800
score 13.211869

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