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Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin

Betulinic acid, 3β-hydroxy-lup-20(29)-ene-28-oic acid (1), is a natural product which can be isolated from several genus of higher plants. Betulinic acid has been shown to exhibit a variety of biological activities. It was found to be an excellent anti-tumor agent due to its unique in vitro and in v...

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Main Author: Yasin, Yamin
Format: Research Reports
Language:English
Published: Research Management Institute (RMI) 2011
Online Access:http://ir.uitm.edu.my/id/eprint/16844/2/LP_YAMIN%20YASIN%20RMI%2011_5.pdf
http://ir.uitm.edu.my/id/eprint/16844/
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spelling my.uitm.ir.168442019-02-06T07:44:47Z http://ir.uitm.edu.my/id/eprint/16844/ Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin Yasin, Yamin Betulinic acid, 3β-hydroxy-lup-20(29)-ene-28-oic acid (1), is a natural product which can be isolated from several genus of higher plants. Betulinic acid has been shown to exhibit a variety of biological activities. It was found to be an excellent anti-tumor agent due to its unique in vitro and in vivo cytotoxicity profile. Betulinic acid was also found to have activity and inhibition against human immunodeficiency virus (HIV) replication in lymphocyte cells, blockage of HIV-1 entry into cells and cytotoxicity against a variety of cultured human tumor cells (Bringmann et al., 1997). Research Management Institute (RMI) 2011 Research Reports NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/16844/2/LP_YAMIN%20YASIN%20RMI%2011_5.pdf Yasin, Yamin (2011) Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin. [Research Reports] (Unpublished)
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
description Betulinic acid, 3β-hydroxy-lup-20(29)-ene-28-oic acid (1), is a natural product which can be isolated from several genus of higher plants. Betulinic acid has been shown to exhibit a variety of biological activities. It was found to be an excellent anti-tumor agent due to its unique in vitro and in vivo cytotoxicity profile. Betulinic acid was also found to have activity and inhibition against human immunodeficiency virus (HIV) replication in lymphocyte cells, blockage of HIV-1 entry into cells and cytotoxicity against a variety of cultured human tumor cells (Bringmann et al., 1997).
format Research Reports
author Yasin, Yamin
spellingShingle Yasin, Yamin
Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
author_facet Yasin, Yamin
author_sort Yasin, Yamin
title Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
title_short Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
title_full Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
title_fullStr Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
title_full_unstemmed Enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / Yamin Yasin
title_sort enzymatic reaction of betulinic acid with acyl chloride: synthesis of anti-cancer compound / yamin yasin
publisher Research Management Institute (RMI)
publishDate 2011
url http://ir.uitm.edu.my/id/eprint/16844/2/LP_YAMIN%20YASIN%20RMI%2011_5.pdf
http://ir.uitm.edu.my/id/eprint/16844/
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score 13.211869

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