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Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul

Type 2 diabetes mellitus (T2DM) and its complications have become a major public health concern in many countries. Around the world, diabetes prevalence in adults aged 20 and over 4 percent in 1995 and it is expected to increase to 5.4 percent in 2030 with the developing countries have a slightly hi...

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Main Author: Kamisul, Muhd Hafizi
Format: Thesis
Language:English
Published: 2013
Subjects:
Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Pharmaceutical chemistry
Online Access:https://ir.uitm.edu.my/id/eprint/110422/1/110422.PDF
https://ir.uitm.edu.my/id/eprint/110422/
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spelling my.uitm.ir.1104222025-02-21T23:55:32Z https://ir.uitm.edu.my/id/eprint/110422/ Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul Kamisul, Muhd Hafizi Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Pharmaceutical chemistry Type 2 diabetes mellitus (T2DM) and its complications have become a major public health concern in many countries. Around the world, diabetes prevalence in adults aged 20 and over 4 percent in 1995 and it is expected to increase to 5.4 percent in 2030 with the developing countries have a slightly higher prevalence than developed countries. In this study, th cytotoxic effect of banana soft pith (BSP) (Musa paradisiaca) hexane extract was evaluated on primary mouse embryonic fibroblast cell (3T3-Ll). This study found that hexane extract of BSP (HA) markedly inhibit the proliferation of 3T3-Ll adipocytes at high concentration. The cell population was visually assessed using laser scanning confocal microscopy following AO/PI staining which shows consistent result with cytotoxicity study with prominent reduction of viable cell. As a conclusion, this study suggested that BSP extract has potential therapeutic benefit towards T2DM that require further investigation. 2013 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/110422/1/110422.PDF Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul. (2013) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Pharmaceutical chemistry
spellingShingle Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Pharmaceutical chemistry
Kamisul, Muhd Hafizi
Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
description Type 2 diabetes mellitus (T2DM) and its complications have become a major public health concern in many countries. Around the world, diabetes prevalence in adults aged 20 and over 4 percent in 1995 and it is expected to increase to 5.4 percent in 2030 with the developing countries have a slightly higher prevalence than developed countries. In this study, th cytotoxic effect of banana soft pith (BSP) (Musa paradisiaca) hexane extract was evaluated on primary mouse embryonic fibroblast cell (3T3-Ll). This study found that hexane extract of BSP (HA) markedly inhibit the proliferation of 3T3-Ll adipocytes at high concentration. The cell population was visually assessed using laser scanning confocal microscopy following AO/PI staining which shows consistent result with cytotoxicity study with prominent reduction of viable cell. As a conclusion, this study suggested that BSP extract has potential therapeutic benefit towards T2DM that require further investigation.
format Thesis
author Kamisul, Muhd Hafizi
author_facet Kamisul, Muhd Hafizi
author_sort Kamisul, Muhd Hafizi
title Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
title_short Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
title_full Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
title_fullStr Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
title_full_unstemmed Antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3T3-L1) / Muhd Hafizi Kamisul
title_sort antiproliferative properties of musa paradisiaca cv (awak) hexane extract towards primary mouse embryonic fibroblast cell (3t3-l1) / muhd hafizi kamisul
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/110422/1/110422.PDF
https://ir.uitm.edu.my/id/eprint/110422/
_version_ 1825165187622109184
score 13.239859

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