Cover Image

Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin

Skin, hair, nail and subcutaneous tissues in human and animal are subjected to infection by several organisms mainly fungi such as dermatophytes which causes dermatophytoses. Dermatophytoses are one of the most recurrent skin diseases of human, pets and livestock. The appearance of antifungal resist...

Full description

Saved in:
Bibliographic Details
Main Author: Md Yasin, Ahmad Syamil
Format: Thesis
Language:English
Published: 2013
Subjects:
Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Online Access:https://ir.uitm.edu.my/id/eprint/110330/1/110330.PDF
https://ir.uitm.edu.my/id/eprint/110330/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.110330
record_format eprints
spelling my.uitm.ir.1103302025-02-18T17:47:15Z https://ir.uitm.edu.my/id/eprint/110330/ Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin Md Yasin, Ahmad Syamil Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Skin, hair, nail and subcutaneous tissues in human and animal are subjected to infection by several organisms mainly fungi such as dermatophytes which causes dermatophytoses. Dermatophytoses are one of the most recurrent skin diseases of human, pets and livestock. The appearance of antifungal resistance fungus has lowered the success rates of antifungal therapy thus becoming a major concern worldwide. This has resulted in the re-evaluation of the therapeutic use of ancient remedies including honey. The antimicrobial activity of honey has been associated with its osmolarity, acidity, hydrogen peroxide, and non-hydrogen peroxide components. The aim of our study was to investigate the potential of selected Malaysian honeys namely Tualang, Acacia, Nenas and Kelulut as antifungal agent against 2 types of dermatophytes which were Trichophyton mentagrophytes and Trichophyton rubrum. Manuka honey and Artificial sugar were used as comparison. The antifungal activity was examined by determining the MIC using the broth dilution assay on microtitre plates while MFC was determined by re-inoculation into agar plates from a well with each concentration of honey where fungal growth was inhibited (from the broth of MIC assay). The honey samples were tested at the concentrations of 70%, 60%, 50%, 25%, 12.5%, 6.25%, 3.1 %, 1.6%, 0.8%, 0.4%, 0.2% and 0.1 % (v/v) dilution. The result showed that all tested honey including Artificial sugar had antifungal activity against Tmentagrophytes and T'rubrum. Manuka honey needed MIC values of 51 % (v/v) to inhibit T.mentagrophytes and 53% (v/v) for T.rubrum. 2013 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/110330/1/110330.PDF Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin. (2013) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
spellingShingle Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Md Yasin, Ahmad Syamil
Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
description Skin, hair, nail and subcutaneous tissues in human and animal are subjected to infection by several organisms mainly fungi such as dermatophytes which causes dermatophytoses. Dermatophytoses are one of the most recurrent skin diseases of human, pets and livestock. The appearance of antifungal resistance fungus has lowered the success rates of antifungal therapy thus becoming a major concern worldwide. This has resulted in the re-evaluation of the therapeutic use of ancient remedies including honey. The antimicrobial activity of honey has been associated with its osmolarity, acidity, hydrogen peroxide, and non-hydrogen peroxide components. The aim of our study was to investigate the potential of selected Malaysian honeys namely Tualang, Acacia, Nenas and Kelulut as antifungal agent against 2 types of dermatophytes which were Trichophyton mentagrophytes and Trichophyton rubrum. Manuka honey and Artificial sugar were used as comparison. The antifungal activity was examined by determining the MIC using the broth dilution assay on microtitre plates while MFC was determined by re-inoculation into agar plates from a well with each concentration of honey where fungal growth was inhibited (from the broth of MIC assay). The honey samples were tested at the concentrations of 70%, 60%, 50%, 25%, 12.5%, 6.25%, 3.1 %, 1.6%, 0.8%, 0.4%, 0.2% and 0.1 % (v/v) dilution. The result showed that all tested honey including Artificial sugar had antifungal activity against Tmentagrophytes and T'rubrum. Manuka honey needed MIC values of 51 % (v/v) to inhibit T.mentagrophytes and 53% (v/v) for T.rubrum.
format Thesis
author Md Yasin, Ahmad Syamil
author_facet Md Yasin, Ahmad Syamil
author_sort Md Yasin, Ahmad Syamil
title Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
title_short Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
title_full Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
title_fullStr Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
title_full_unstemmed Antifungal activity of Malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / Ahmad Syamil Md Yasin
title_sort antifungal activity of malaysian honeys against trichophyton mentagrophytes and trichophyton rubrum / ahmad syamil md yasin
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/110330/1/110330.PDF
https://ir.uitm.edu.my/id/eprint/110330/
_version_ 1825165179274395648
score 13.239859

Similar Items