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Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman

As we know, 'tea tarik' is one of the cultures in Malaysia. However, high calories and sweet taste of 'tea tarik' draw public concern for adverse health effects as it is prone to cause obesity and diabetes. Thus, RebA Tea tarik is produce to overcome these circumstances. RebA Tea...

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Main Author: Kamarulzaman, Nurul Diyana
Format: Thesis
Language:English
Published: 2013
Subjects:
Pharmacopoeias
Online Access:https://ir.uitm.edu.my/id/eprint/109579/1/109579.PDF
https://ir.uitm.edu.my/id/eprint/109579/
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spelling my.uitm.ir.1095792025-02-14T11:52:04Z https://ir.uitm.edu.my/id/eprint/109579/ Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman Kamarulzaman, Nurul Diyana Pharmacopoeias As we know, 'tea tarik' is one of the cultures in Malaysia. However, high calories and sweet taste of 'tea tarik' draw public concern for adverse health effects as it is prone to cause obesity and diabetes. Thus, RebA Tea tarik is produce to overcome these circumstances. RebA Tea tarik is expected to be a healthy and tasty tea tarik formulation which is safe to be consumed by the 'tea tarik' lover eventhough patient with diabetes. Therefore, this research project is performed to determine cytotoxicity of different component in RebaTea tarik at 24 Hours observation in normal human hepatic cells (WRL-68 cells). WRL-68 cells were treated with six concentration of different component in RebA Tea tarik and cytotoxicity was measured by using MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay. After 24 hours observation, all cells treated with rebaudioside A, skimmed milk, tea extract, and RebA Tea Tarik formulation showed low cytotoxicity level. Increasing pattern of cell viability was demonstrated by cells treated with skimmed milk which was above 100% while decreasing pattern was observed with cells treated with rebaudioside A which was not less than 82%. The cytotoxicity level of all components did not fall below than 70% cell viability. Based on this study, it can be concluded that component in RebA Tea tarik did not exhibit any harm or toxic to WRL-68 cells and this formulation is safe to be consumed by the 'tea tarik' lover. 2013 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/109579/1/109579.PDF Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman. (2013) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Pharmacopoeias
spellingShingle Pharmacopoeias
Kamarulzaman, Nurul Diyana
Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
description As we know, 'tea tarik' is one of the cultures in Malaysia. However, high calories and sweet taste of 'tea tarik' draw public concern for adverse health effects as it is prone to cause obesity and diabetes. Thus, RebA Tea tarik is produce to overcome these circumstances. RebA Tea tarik is expected to be a healthy and tasty tea tarik formulation which is safe to be consumed by the 'tea tarik' lover eventhough patient with diabetes. Therefore, this research project is performed to determine cytotoxicity of different component in RebaTea tarik at 24 Hours observation in normal human hepatic cells (WRL-68 cells). WRL-68 cells were treated with six concentration of different component in RebA Tea tarik and cytotoxicity was measured by using MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay. After 24 hours observation, all cells treated with rebaudioside A, skimmed milk, tea extract, and RebA Tea Tarik formulation showed low cytotoxicity level. Increasing pattern of cell viability was demonstrated by cells treated with skimmed milk which was above 100% while decreasing pattern was observed with cells treated with rebaudioside A which was not less than 82%. The cytotoxicity level of all components did not fall below than 70% cell viability. Based on this study, it can be concluded that component in RebA Tea tarik did not exhibit any harm or toxic to WRL-68 cells and this formulation is safe to be consumed by the 'tea tarik' lover.
format Thesis
author Kamarulzaman, Nurul Diyana
author_facet Kamarulzaman, Nurul Diyana
author_sort Kamarulzaman, Nurul Diyana
title Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
title_short Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
title_full Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
title_fullStr Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
title_full_unstemmed Cytotoxicity of component in rebatea tarik at 24 hours observation in WRL-68 cells / Nurul Diyana Kamarulzaman
title_sort cytotoxicity of component in rebatea tarik at 24 hours observation in wrl-68 cells / nurul diyana kamarulzaman
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/109579/1/109579.PDF
https://ir.uitm.edu.my/id/eprint/109579/
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score 13.239859

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