Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry

Aging is the process whereby cognitive function starts to decline. This decline gives a bad impact in social and economic aspects and cause memory loss problem. Dysfunction of neurons in the brain will lead to the declining of cognitive observed in elderly people and those who suffered from Alzheime...

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Main Author: Zamasry, Syafiqah
Format: Thesis
Language:English
Published: 2013
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Online Access:https://ir.uitm.edu.my/id/eprint/109534/1/109534.PDF
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spelling my.uitm.ir.1095342025-02-13T23:57:30Z https://ir.uitm.edu.my/id/eprint/109534/ Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry Zamasry, Syafiqah Pharmacopoeias Aging is the process whereby cognitive function starts to decline. This decline gives a bad impact in social and economic aspects and cause memory loss problem. Dysfunction of neurons in the brain will lead to the declining of cognitive observed in elderly people and those who suffered from Alzheimer's disease (AD). There are many methods and products introduced in the market in order to overcome the problem of memory loss. Since there are still not many studies done on the beneficial effect of chocolate in enhancing memory, the purpose of this study is to test memory-enhancing chocolate available in the market by using radial arm maze (RAM) model in mice. Mice subjects (n=5) were administered orally with memory-enhancing chocolate· ( dosage of 200 mg/kg and 400 mg/kg), piracetam 200 mg/kg as positive control and normal saline as negative control for 14 days prior to RAM experiment for three days. The results of this study showed an improvement in mice of piracetam group as they learn and store the information as memory. In addition, only piracetam are significantly different from the memory­ enhancing chocolate and negative control. This is further supported by previous study that found piracetam is a nootropics drug that exhibits neuroprotective properties. 2013 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/109534/1/109534.PDF Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry. (2013) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Pharmacopoeias
spellingShingle Pharmacopoeias
Zamasry, Syafiqah
Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
description Aging is the process whereby cognitive function starts to decline. This decline gives a bad impact in social and economic aspects and cause memory loss problem. Dysfunction of neurons in the brain will lead to the declining of cognitive observed in elderly people and those who suffered from Alzheimer's disease (AD). There are many methods and products introduced in the market in order to overcome the problem of memory loss. Since there are still not many studies done on the beneficial effect of chocolate in enhancing memory, the purpose of this study is to test memory-enhancing chocolate available in the market by using radial arm maze (RAM) model in mice. Mice subjects (n=5) were administered orally with memory-enhancing chocolate· ( dosage of 200 mg/kg and 400 mg/kg), piracetam 200 mg/kg as positive control and normal saline as negative control for 14 days prior to RAM experiment for three days. The results of this study showed an improvement in mice of piracetam group as they learn and store the information as memory. In addition, only piracetam are significantly different from the memory­ enhancing chocolate and negative control. This is further supported by previous study that found piracetam is a nootropics drug that exhibits neuroprotective properties.
format Thesis
author Zamasry, Syafiqah
author_facet Zamasry, Syafiqah
author_sort Zamasry, Syafiqah
title Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
title_short Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
title_full Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
title_fullStr Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
title_full_unstemmed Test of memory-enhancing chocolate in Swiss mice by using radial arm maze / Syafiqah Zamasry
title_sort test of memory-enhancing chocolate in swiss mice by using radial arm maze / syafiqah zamasry
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/109534/1/109534.PDF
https://ir.uitm.edu.my/id/eprint/109534/
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score 13.239859