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The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh

The endophytic fungi were investigated previously to produce promising compound as antimicrobial agent. However, the antimicrobial activity of marine endophytic fungi isolated from marine plants have not been further explored and documented. In present study, six marine endophytic fungi extracts (PA...

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Main Author: Mohd Musleh, Mohamad Syafiq
Format: Thesis
Language:English
Published: 2013
Subjects:
Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Online Access:https://ir.uitm.edu.my/id/eprint/109392/1/109392.PDF
https://ir.uitm.edu.my/id/eprint/109392/
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spelling my.uitm.ir.1093922025-01-20T09:44:41Z https://ir.uitm.edu.my/id/eprint/109392/ The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh Mohd Musleh, Mohamad Syafiq Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) The endophytic fungi were investigated previously to produce promising compound as antimicrobial agent. However, the antimicrobial activity of marine endophytic fungi isolated from marine plants have not been further explored and documented. In present study, six marine endophytic fungi extracts (PAI, PA2, PA3, PA4, PAS, PA6) were isolated form Malaysian marine seaweed, Padina australis and growth in two media (PDA, PDA + 3% AS). The endophyte extracts (PAI PDA, PAI 3%, PA2 PDA, PA2 3%, PA3 PDA, PA3 3%, PA4 PDA, PA4 3%, PAS PDA, PAS 3%, PA6 PDA, PA6 3%) were tested for antibacterial (six common pathogenic bacteria) activities and antifungal (three common pathogenic fungi) activities. From the result on antibacterial test three extracts that were extracted from marine endophytic fungi growth in PDA media (PAI PDA, PA2 PDA, PA3 PDA) are much better because they have the inhibition effect to three bacteria out of six bacteria tested. This result indicates that marine endophytic fungi have antibacterial activity. The antifungal test showed out of 12 (PA I PDA, PA I 3%, PA2 PDA, PA3 PDA, PA3 3%, PA4 PDA, PA4 3%, PAS PDA, PAS 3%, PA6 PDA , PA6 3%) four extract (PAI PDA, PAI 3%, PA2 3% and PA4 3% ) was gave the antifungal effect and endophytes that were growth in PDA+3% AS were better to give antifungal effect toward fungi tested where three of endophyte growth in PDA+3% AS (PAI 3%, PA2 3% and PA4 3%) were inhibited growth of fungi tested compared to PDA only one extract (PAI PDA) able to give antifungal effect. The result manifested that marine endophytic fungi have antifungal activity. Therefore these marine endophytic fungi isolated from Padina australis might have a great potential to be antimicrobial agent due to bioactivity of its extracts. 2013 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/109392/1/109392.PDF The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh. (2013) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
spellingShingle Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Mohd Musleh, Mohamad Syafiq
The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
description The endophytic fungi were investigated previously to produce promising compound as antimicrobial agent. However, the antimicrobial activity of marine endophytic fungi isolated from marine plants have not been further explored and documented. In present study, six marine endophytic fungi extracts (PAI, PA2, PA3, PA4, PAS, PA6) were isolated form Malaysian marine seaweed, Padina australis and growth in two media (PDA, PDA + 3% AS). The endophyte extracts (PAI PDA, PAI 3%, PA2 PDA, PA2 3%, PA3 PDA, PA3 3%, PA4 PDA, PA4 3%, PAS PDA, PAS 3%, PA6 PDA, PA6 3%) were tested for antibacterial (six common pathogenic bacteria) activities and antifungal (three common pathogenic fungi) activities. From the result on antibacterial test three extracts that were extracted from marine endophytic fungi growth in PDA media (PAI PDA, PA2 PDA, PA3 PDA) are much better because they have the inhibition effect to three bacteria out of six bacteria tested. This result indicates that marine endophytic fungi have antibacterial activity. The antifungal test showed out of 12 (PA I PDA, PA I 3%, PA2 PDA, PA3 PDA, PA3 3%, PA4 PDA, PA4 3%, PAS PDA, PAS 3%, PA6 PDA , PA6 3%) four extract (PAI PDA, PAI 3%, PA2 3% and PA4 3% ) was gave the antifungal effect and endophytes that were growth in PDA+3% AS were better to give antifungal effect toward fungi tested where three of endophyte growth in PDA+3% AS (PAI 3%, PA2 3% and PA4 3%) were inhibited growth of fungi tested compared to PDA only one extract (PAI PDA) able to give antifungal effect. The result manifested that marine endophytic fungi have antifungal activity. Therefore these marine endophytic fungi isolated from Padina australis might have a great potential to be antimicrobial agent due to bioactivity of its extracts.
format Thesis
author Mohd Musleh, Mohamad Syafiq
author_facet Mohd Musleh, Mohamad Syafiq
author_sort Mohd Musleh, Mohamad Syafiq
title The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
title_short The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
title_full The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
title_fullStr The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
title_full_unstemmed The antimicrobial activity of marine endophytic fungi from padina australis / Mohamad Syafiq Mohd Musleh
title_sort antimicrobial activity of marine endophytic fungi from padina australis / mohamad syafiq mohd musleh
publishDate 2013
url https://ir.uitm.edu.my/id/eprint/109392/1/109392.PDF
https://ir.uitm.edu.my/id/eprint/109392/
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score 13.235796

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