Cover Image

Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]

COVID-19 infection results in a disease ranging from asymptomatic to severe pneumonia and death. This case report aimed to describe the autopsy findings of a COVID-19 positive patient with concurrent septicaemia associated with gastrointestinal tract perforation. We report a case of a 29-year-old pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Rahim, Razuin, Nor Azmal, Nur Ilyani, Mohd Kornain, Noor Kaslina, Abdul Aziz, Mardiana
Format: Article
Language:English
Published: Faculty of Medicine 2024
Subjects:
Communicable diseases and public health
Online Access:https://ir.uitm.edu.my/id/eprint/101503/1/101503.pdf
https://ir.uitm.edu.my/id/eprint/101503/
http://jchs-medicine.uitm.edu.my/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.101503
record_format eprints
spelling my.uitm.ir.1015032024-09-05T09:26:48Z https://ir.uitm.edu.my/id/eprint/101503/ Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.] jchs Rahim, Razuin Nor Azmal, Nur Ilyani Mohd Kornain, Noor Kaslina Abdul Aziz, Mardiana Communicable diseases and public health COVID-19 infection results in a disease ranging from asymptomatic to severe pneumonia and death. This case report aimed to describe the autopsy findings of a COVID-19 positive patient with concurrent septicaemia associated with gastrointestinal tract perforation. We report a case of a 29-year-old prison detainee who collapsed and died at a hospital prior to a surgical procedure. The diagnosis of COVID-19 was confirmed by RT-PCR testing on postmortem nasopharyngeal swabs. Apart from fever, there was no COVID-19 symptoms reported by the patient. The autopsy revealed massive suppurative ascites with evidence of septicaemia and large bowel perforations. The lungs’ macroscopy did not show distinct pneumonic changes, however, microscopically, organizing pneumonia, perivascular lymphocytic infiltrates and increased number of megakyocytes were present. Vascular pathology such as endothelialitis and thrombosis were also seen in other organs. We affirmed the spectrum of pathological changes associated with COVID-19 infection from the previous studies. This case report highlighted that the detrimental microscopic changes could be present irrespective of the degree of severity of the clinical symptoms. Faculty of Medicine 2024-09 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/101503/1/101503.pdf Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]. (2024) Journal of Clinical and Health Sciences (JCHS) <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences_=28JCHS=29/>, 9 (2). pp. 75-81. ISSN 0127-984X http://jchs-medicine.uitm.edu.my/
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Communicable diseases and public health
spellingShingle Communicable diseases and public health
Rahim, Razuin
Nor Azmal, Nur Ilyani
Mohd Kornain, Noor Kaslina
Abdul Aziz, Mardiana
Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
description COVID-19 infection results in a disease ranging from asymptomatic to severe pneumonia and death. This case report aimed to describe the autopsy findings of a COVID-19 positive patient with concurrent septicaemia associated with gastrointestinal tract perforation. We report a case of a 29-year-old prison detainee who collapsed and died at a hospital prior to a surgical procedure. The diagnosis of COVID-19 was confirmed by RT-PCR testing on postmortem nasopharyngeal swabs. Apart from fever, there was no COVID-19 symptoms reported by the patient. The autopsy revealed massive suppurative ascites with evidence of septicaemia and large bowel perforations. The lungs’ macroscopy did not show distinct pneumonic changes, however, microscopically, organizing pneumonia, perivascular lymphocytic infiltrates and increased number of megakyocytes were present. Vascular pathology such as endothelialitis and thrombosis were also seen in other organs. We affirmed the spectrum of pathological changes associated with COVID-19 infection from the previous studies. This case report highlighted that the detrimental microscopic changes could be present irrespective of the degree of severity of the clinical symptoms.
format Article
author Rahim, Razuin
Nor Azmal, Nur Ilyani
Mohd Kornain, Noor Kaslina
Abdul Aziz, Mardiana
author_facet Rahim, Razuin
Nor Azmal, Nur Ilyani
Mohd Kornain, Noor Kaslina
Abdul Aziz, Mardiana
author_sort Rahim, Razuin
title Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
title_short Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
title_full Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
title_fullStr Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
title_full_unstemmed Histopathological findings in COVID-19 with concurrent septicaemia: an autopsy case report / Razuin Rahimi ... [et al.]
title_sort histopathological findings in covid-19 with concurrent septicaemia: an autopsy case report / razuin rahimi ... [et al.]
publisher Faculty of Medicine
publishDate 2024
url https://ir.uitm.edu.my/id/eprint/101503/1/101503.pdf
https://ir.uitm.edu.my/id/eprint/101503/
http://jchs-medicine.uitm.edu.my/
_version_ 1811598220313231360
score 13.211869

Similar Items