Cover Image

Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis

This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed ext...

Full description

Saved in:
Bibliographic Details
Main Author: Darnalis, Nur Mardhiya
Format: Thesis
Language:English
Published: 2007
Subjects:
Examination of the blood
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF
https://ir.uitm.edu.my/id/eprint/100069/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.100069
record_format eprints
spelling my.uitm.ir.1000692024-08-26T05:05:17Z https://ir.uitm.edu.my/id/eprint/100069/ Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis Darnalis, Nur Mardhiya Examination of the blood RM Therapeutics. Pharmacology RS Pharmacy and materia medica This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed extract of Hylocereus polyrhizus was administered by gavage with the use of oral needle. Blood samples were obtained by cardiac puncture. No mortality and clinical signs of toxicity were observed upon administration of HP for both acute and sub acute toxicity studies. Blood analysis showed significant changes in certain blood parameters. In the acute toxicity study, the blood levels of urea were significantly lower in the treatment group. In the sub acute toxicity study, there were no significance differences between both groups for all parameters. It can be concluded that the flesh's extract of HP can affect certain blood parameters and possibly has hepatoprotective effects. Further studies are needed to validate these effects in order to ensure the safe consumption of HP fruit. 2007 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis. (2007) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Examination of the blood
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
spellingShingle Examination of the blood
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Darnalis, Nur Mardhiya
Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
description This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed extract of Hylocereus polyrhizus was administered by gavage with the use of oral needle. Blood samples were obtained by cardiac puncture. No mortality and clinical signs of toxicity were observed upon administration of HP for both acute and sub acute toxicity studies. Blood analysis showed significant changes in certain blood parameters. In the acute toxicity study, the blood levels of urea were significantly lower in the treatment group. In the sub acute toxicity study, there were no significance differences between both groups for all parameters. It can be concluded that the flesh's extract of HP can affect certain blood parameters and possibly has hepatoprotective effects. Further studies are needed to validate these effects in order to ensure the safe consumption of HP fruit.
format Thesis
author Darnalis, Nur Mardhiya
author_facet Darnalis, Nur Mardhiya
author_sort Darnalis, Nur Mardhiya
title Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_short Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_full Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_fullStr Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_full_unstemmed Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_sort effects of hylocereus polyrhizus flesh on blood parameters in mice / nur mardhiya darnalis
publishDate 2007
url https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF
https://ir.uitm.edu.my/id/eprint/100069/
_version_ 1808976077075251200
score 13.211869

Similar Items