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Quorum sensing: An imperative longevity weapon in bacteria

Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinduce...

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Main Authors: Pawar, Shrikant, Lahiri, Chandrajit *
Format: Article
Language:English
Published: Academic Journals 2018
Subjects:
QR Microbiology
Online Access:http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf
http://eprints.sunway.edu.my/900/
http://doi.org/10.5897/AJMR2017.8751
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spelling my.sunway.eprints.9002019-04-26T07:11:23Z http://eprints.sunway.edu.my/900/ Quorum sensing: An imperative longevity weapon in bacteria Pawar, Shrikant Lahiri, Chandrajit * QR Microbiology Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinducers like acyl-homoserine lactone-signaling molecules to regulate cell population density. Different species of bacteria utilize different QS molecules to regulate its gene expression. A free-living marine bacterium, Vibrio harveyi, uses two QS system to control the density-dependent expression of bioluminescence (lux), commonly classified as sensor and autoinducer system. In Pseudomonas aeruginosa, QS not only controls virulence factor production but also biofilm formation. It is comprised two hierarchically organised systems, each consisting of an autoinducer synthetase (LasI/RhlI) and a corresponding regulator protein (LasR/RhlR). Biofilms produced by Pseudomonas, under control of QS, are ubiquitous in nature and contribute towards colonizations in patients of cystic fibrosis. Other organisms like Haemophilus influenzae and Streptococcus also utilize QS mechanism to control virulence in otitis and endocarditic decay. Overall, QS plays a major role in controlling bacterial economy. It is a simple, practical and effective mechanism of production and control. If the concentration of enzyme is critical, bacteria can sense it and perform a prompt activation or repression of certain target genes for controlling its environment. This review focuses on the QS mechanisms and their role in the survival of few important bacterial species. Academic Journals 2018-01-05 Article PeerReviewed text en http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf Pawar, Shrikant and Lahiri, Chandrajit * (2018) Quorum sensing: An imperative longevity weapon in bacteria. African Journal of Microbiology Research, 12 (4). pp. 96-104. ISSN 1996-0808 http://doi.org/10.5897/AJMR2017.8751 doi:10.5897/AJMR2017.8751
institution Sunway University
building Sunway Campus Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Sunway University
content_source Sunway Institutional Repository
url_provider http://eprints.sunway.edu.my/
language English
topic QR Microbiology
spellingShingle QR Microbiology
Pawar, Shrikant
Lahiri, Chandrajit *
Quorum sensing: An imperative longevity weapon in bacteria
description Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinducers like acyl-homoserine lactone-signaling molecules to regulate cell population density. Different species of bacteria utilize different QS molecules to regulate its gene expression. A free-living marine bacterium, Vibrio harveyi, uses two QS system to control the density-dependent expression of bioluminescence (lux), commonly classified as sensor and autoinducer system. In Pseudomonas aeruginosa, QS not only controls virulence factor production but also biofilm formation. It is comprised two hierarchically organised systems, each consisting of an autoinducer synthetase (LasI/RhlI) and a corresponding regulator protein (LasR/RhlR). Biofilms produced by Pseudomonas, under control of QS, are ubiquitous in nature and contribute towards colonizations in patients of cystic fibrosis. Other organisms like Haemophilus influenzae and Streptococcus also utilize QS mechanism to control virulence in otitis and endocarditic decay. Overall, QS plays a major role in controlling bacterial economy. It is a simple, practical and effective mechanism of production and control. If the concentration of enzyme is critical, bacteria can sense it and perform a prompt activation or repression of certain target genes for controlling its environment. This review focuses on the QS mechanisms and their role in the survival of few important bacterial species.
format Article
author Pawar, Shrikant
Lahiri, Chandrajit *
author_facet Pawar, Shrikant
Lahiri, Chandrajit *
author_sort Pawar, Shrikant
title Quorum sensing: An imperative longevity weapon in bacteria
title_short Quorum sensing: An imperative longevity weapon in bacteria
title_full Quorum sensing: An imperative longevity weapon in bacteria
title_fullStr Quorum sensing: An imperative longevity weapon in bacteria
title_full_unstemmed Quorum sensing: An imperative longevity weapon in bacteria
title_sort quorum sensing: an imperative longevity weapon in bacteria
publisher Academic Journals
publishDate 2018
url http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf
http://eprints.sunway.edu.my/900/
http://doi.org/10.5897/AJMR2017.8751
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score 13.211869

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