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Viral determinants and vector competence of Zika Virus transmission

Zika virus (ZIKV) has emerged as a new global health threat. Since its first discovery in Zika forest in Uganda, this virus has been isolated from several mosquito species, including Aedes aegypti and Aedes albopictus. The geographical distribution of these mosquito species across tropical and subtr...

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Main Authors: Tham, Hong-Wai, Balasubramaniam, Vinod, Ooi, Man K., Chew, Miaw Fang *
Format: Article
Language:English
Published: Frontiers Media 2018
Subjects:
QR355 Virology
RA0421 Public health. Hygiene. Preventive Medicine
Online Access:http://eprints.sunway.edu.my/883/1/Chew%20Miaw%20Fang%20Viral%20determinants%20and%20vector%20competence%20of%20Zika.pdf
http://eprints.sunway.edu.my/883/
http://www.frontiersin.org
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spelling my.sunway.eprints.8832018-08-13T04:06:09Z http://eprints.sunway.edu.my/883/ Viral determinants and vector competence of Zika Virus transmission Tham, Hong-Wai Balasubramaniam, Vinod Ooi, Man K. Chew, Miaw Fang * QR355 Virology RA0421 Public health. Hygiene. Preventive Medicine Zika virus (ZIKV) has emerged as a new global health threat. Since its first discovery in Zika forest in Uganda, this virus has been isolated from several mosquito species, including Aedes aegypti and Aedes albopictus. The geographical distribution of these mosquito species across tropical and subtropical regions has led to several outbreaks, including the recent pandemic in Brazil, followed by the Pacific islands and other areas of North and South America. This has gained attention of the scientific community to elucidate the epidemiology and transmission of ZIKV. Despite its strong attention on clinical aspects for healthcare professionals, the relationships between ZIKV and its principal vectors, A. aegypti and A. albopictus, have not gained substantial interest in the scientific research community. As such, this review aims to summarize the current knowledge on ZIKV tropism and some important mechanisms which may be employed by the virus for effective strategies on viral survival in mosquitoes. In addition, this review identifies the areas of research that should be placed attention to, for which to be exploited for novel mosquito control strategies. Frontiers Media 2018-05-23 Article PeerReviewed text en http://eprints.sunway.edu.my/883/1/Chew%20Miaw%20Fang%20Viral%20determinants%20and%20vector%20competence%20of%20Zika.pdf Tham, Hong-Wai and Balasubramaniam, Vinod and Ooi, Man K. and Chew, Miaw Fang * (2018) Viral determinants and vector competence of Zika Virus transmission. Frontiers in Microbiology, 9 (1040). ISSN 1664-302X http://www.frontiersin.org doi:10.3389/fmicb.2018.01040
institution Sunway University
building Sunway Campus Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Sunway University
content_source Sunway Institutional Repository
url_provider http://eprints.sunway.edu.my/
language English
topic QR355 Virology
RA0421 Public health. Hygiene. Preventive Medicine
spellingShingle QR355 Virology
RA0421 Public health. Hygiene. Preventive Medicine
Tham, Hong-Wai
Balasubramaniam, Vinod
Ooi, Man K.
Chew, Miaw Fang *
Viral determinants and vector competence of Zika Virus transmission
description Zika virus (ZIKV) has emerged as a new global health threat. Since its first discovery in Zika forest in Uganda, this virus has been isolated from several mosquito species, including Aedes aegypti and Aedes albopictus. The geographical distribution of these mosquito species across tropical and subtropical regions has led to several outbreaks, including the recent pandemic in Brazil, followed by the Pacific islands and other areas of North and South America. This has gained attention of the scientific community to elucidate the epidemiology and transmission of ZIKV. Despite its strong attention on clinical aspects for healthcare professionals, the relationships between ZIKV and its principal vectors, A. aegypti and A. albopictus, have not gained substantial interest in the scientific research community. As such, this review aims to summarize the current knowledge on ZIKV tropism and some important mechanisms which may be employed by the virus for effective strategies on viral survival in mosquitoes. In addition, this review identifies the areas of research that should be placed attention to, for which to be exploited for novel mosquito control strategies.
format Article
author Tham, Hong-Wai
Balasubramaniam, Vinod
Ooi, Man K.
Chew, Miaw Fang *
author_facet Tham, Hong-Wai
Balasubramaniam, Vinod
Ooi, Man K.
Chew, Miaw Fang *
author_sort Tham, Hong-Wai
title Viral determinants and vector competence of Zika Virus transmission
title_short Viral determinants and vector competence of Zika Virus transmission
title_full Viral determinants and vector competence of Zika Virus transmission
title_fullStr Viral determinants and vector competence of Zika Virus transmission
title_full_unstemmed Viral determinants and vector competence of Zika Virus transmission
title_sort viral determinants and vector competence of zika virus transmission
publisher Frontiers Media
publishDate 2018
url http://eprints.sunway.edu.my/883/1/Chew%20Miaw%20Fang%20Viral%20determinants%20and%20vector%20competence%20of%20Zika.pdf
http://eprints.sunway.edu.my/883/
http://www.frontiersin.org
_version_ 1644324425870344192
score 13.211869

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