A tryptophan metabolite made by a gut microbiome eukaryote induces pro-inflammatory T cells

The large intestine harbors microorganisms playing unique roles in host physiology. The beneficial or detrimental outcome of host-microbiome coexistence depends largely on the balance between regulators and responder intestinal CD4+ T cells. We found that ulcerative colitis-like changes in the large...

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Main Authors: Wojciech, Lukasz, Png, Chin Wen, Koh, Eileen Y, Kioh, Dorinda Yan Qin, Deng, Lei, Wang, Ziteng, Wu, Liang Zhe, Hamidinia, Maryam, Tung, Desmond Wh, Zhang, Wei, Pettersson, Sven *, Chan, Eric Chun Yong, Zhang, Yongliang, Tan, Kevin Sw, Gascoigne, Nicholas Rj
Format: Article
Published: EMBO Press 2023
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Online Access:http://eprints.sunway.edu.my/2754/
https://doi.org/10.15252/embj.2022112963
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