Drug-related problems among older people with dementia: A systematic review
Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs). Objective: This systematic review so...
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2023
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my.sunway.eprints.27242024-07-03T08:26:13Z http://eprints.sunway.edu.my/2724/ Drug-related problems among older people with dementia: A systematic review Ng, Qlaementine Xue Qin Long, Chiau Ming * Mohd Shahezwan, Abdul Wahab Tan, Ching Siang Yuda, Ana Hermansyah, Andi RC Internal medicine RM Therapeutics. Pharmacology Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs). Objective: This systematic review sought to identify DRPs due to medication misadventures, including adverse drug reactions (ADRs), and use of inappropriate medications, among patients with dementia or cognitive impairments. Methods: The included studies were retrieved from the electronic databases PubMed and SCOPUS, and a preprint platform (MedRXiv) which were searched from their inception through August 2022. The English-language publications that reported DRPs among dementia patients were included. The JBI Critical Appraisal Tool for quality assessment was used to evaluate the quality of studies included in the review. Results: Overall, 746 distinct articles were identified. Fifteen studies met the inclusion criteria and reported the most common DRPs, which comprised medication misadventures (n = 9), such as ADRs, inappropriate prescription use, and potentially inappropriate medication use (n = 6). Conclusion: This systematic review provides evidence that DRPs are prevalent among dementia patients, particularly the older people. It indicates that medication misadventures such as ADRs and inappropriate drug use, as well as potentially inappropriate medications, are the most prevalent DRPs among older people with dementia. Due to the small number of included studies, however, additional studies are required to improve comprehension about the issue. Elsevier 2023 Article PeerReviewed Ng, Qlaementine Xue Qin and Long, Chiau Ming * and Mohd Shahezwan, Abdul Wahab and Tan, Ching Siang and Yuda, Ana and Hermansyah, Andi (2023) Drug-related problems among older people with dementia: A systematic review. Research in Social and Administrative Pharmacy, 19 (6). pp. 873-881. ISSN 1934-8150 https://doi.org/10.1016/j.sapharm.2023.02.015 10.1016/j.sapharm.2023.02.015 |
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RC Internal medicine RM Therapeutics. Pharmacology Ng, Qlaementine Xue Qin Long, Chiau Ming * Mohd Shahezwan, Abdul Wahab Tan, Ching Siang Yuda, Ana Hermansyah, Andi Drug-related problems among older people with dementia: A systematic review |
| description |
Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs).
Objective: This systematic review sought to identify DRPs due to medication misadventures, including adverse drug reactions (ADRs), and use of inappropriate medications, among patients with dementia or cognitive impairments.
Methods: The included studies were retrieved from the electronic databases PubMed and SCOPUS, and a preprint platform (MedRXiv) which were searched from their inception through August 2022. The English-language publications that reported DRPs among dementia patients were included. The JBI Critical Appraisal Tool for quality assessment was used to evaluate the quality of studies included in the review.
Results: Overall, 746 distinct articles were identified. Fifteen studies met the inclusion criteria and reported the most common DRPs, which comprised medication misadventures (n = 9), such as ADRs, inappropriate prescription use, and potentially inappropriate medication use (n = 6).
Conclusion: This systematic review provides evidence that DRPs are prevalent among dementia patients, particularly the older people. It indicates that medication misadventures such as ADRs and inappropriate drug use, as well as potentially inappropriate medications, are the most prevalent DRPs among older people with dementia. Due to the small number of included studies, however, additional studies are required to improve comprehension about the issue. |
| format |
Article |
| author |
Ng, Qlaementine Xue Qin Long, Chiau Ming * Mohd Shahezwan, Abdul Wahab Tan, Ching Siang Yuda, Ana Hermansyah, Andi |
| author_facet |
Ng, Qlaementine Xue Qin Long, Chiau Ming * Mohd Shahezwan, Abdul Wahab Tan, Ching Siang Yuda, Ana Hermansyah, Andi |
| author_sort |
Ng, Qlaementine Xue Qin |
| title |
Drug-related problems among older people with dementia: A systematic review |
| title_short |
Drug-related problems among older people with dementia: A systematic review |
| title_full |
Drug-related problems among older people with dementia: A systematic review |
| title_fullStr |
Drug-related problems among older people with dementia: A systematic review |
| title_full_unstemmed |
Drug-related problems among older people with dementia: A systematic review |
| title_sort |
drug-related problems among older people with dementia: a systematic review |
| publisher |
Elsevier |
| publishDate |
2023 |
| url |
http://eprints.sunway.edu.my/2724/ https://doi.org/10.1016/j.sapharm.2023.02.015 |
| _version_ |
1804069663165906944 |
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13.211869 |