Staff View: Dual-action potential of cationic cryptides against infections and cancers

Dual-action potential of cationic cryptides against infections and cancers

Cryptides are a subfamily of bioactive peptides embedded latently in their parent proteins and have multiple biological functions. Cationic cryptides could be used as modern drugs in both infectious diseases and cancers because their mechanism of action is less likely to be affected by genetic mutat...

Full description

Saved in:

Bibliographic Details
Main Authors:	Amr Adel, Ahmed Abd El-Aal , Fairen, Angelin Jayakumar , Kavita, Reginald *
Format:	Article
Published:	Elsevier 2023
Subjects:	QD Chemistry RA Public aspects of medicine RC Internal medicine
Online Access:	http://eprints.sunway.edu.my/2696/ https://doi.org/10.1016/j.drudis.2023.103764
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.sunway.eprints.2696
record_format	eprints
spelling	my.sunway.eprints.26962024-06-27T01:02:13Z http://eprints.sunway.edu.my/2696/ Dual-action potential of cationic cryptides against infections and cancers Amr Adel, Ahmed Abd El-Aal * Fairen, Angelin Jayakumar * Kavita, Reginald * QD Chemistry RA Public aspects of medicine RC Internal medicine Cryptides are a subfamily of bioactive peptides embedded latently in their parent proteins and have multiple biological functions. Cationic cryptides could be used as modern drugs in both infectious diseases and cancers because their mechanism of action is less likely to be affected by genetic mutations in the treated cells, therefore addressing a current unmet need in these two areas of medicine. In this review, we present the current understanding of cryptides, methods to mine them sustainably using available online databases and prediction tools, with a particular focus on their antimicrobial and anticancer potential, and their potential applicability in a clinical setting. Elsevier 2023 Article PeerReviewed Amr Adel, Ahmed Abd El-Aal * and Fairen, Angelin Jayakumar * and Kavita, Reginald * (2023) Dual-action potential of cationic cryptides against infections and cancers. Drug Discovery Today, 28 (11). ISSN 1359-6446 https://doi.org/10.1016/j.drudis.2023.103764 10.1016/j.drudis.2023.103764
institution	Sunway University
building	Sunway Campus Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Sunway University
content_source	Sunway Institutional Repository
url_provider	http://eprints.sunway.edu.my/
topic	QD Chemistry RA Public aspects of medicine RC Internal medicine
spellingShingle	QD Chemistry RA Public aspects of medicine RC Internal medicine Amr Adel, Ahmed Abd El-Aal * Fairen, Angelin Jayakumar * Kavita, Reginald * Dual-action potential of cationic cryptides against infections and cancers
description	Cryptides are a subfamily of bioactive peptides embedded latently in their parent proteins and have multiple biological functions. Cationic cryptides could be used as modern drugs in both infectious diseases and cancers because their mechanism of action is less likely to be affected by genetic mutations in the treated cells, therefore addressing a current unmet need in these two areas of medicine. In this review, we present the current understanding of cryptides, methods to mine them sustainably using available online databases and prediction tools, with a particular focus on their antimicrobial and anticancer potential, and their potential applicability in a clinical setting.
format	Article
author	Amr Adel, Ahmed Abd El-Aal * Fairen, Angelin Jayakumar * Kavita, Reginald *
author_facet	Amr Adel, Ahmed Abd El-Aal * Fairen, Angelin Jayakumar * Kavita, Reginald *
author_sort	Amr Adel, Ahmed Abd El-Aal *
title	Dual-action potential of cationic cryptides against infections and cancers
title_short	Dual-action potential of cationic cryptides against infections and cancers
title_full	Dual-action potential of cationic cryptides against infections and cancers
title_fullStr	Dual-action potential of cationic cryptides against infections and cancers
title_full_unstemmed	Dual-action potential of cationic cryptides against infections and cancers
title_sort	dual-action potential of cationic cryptides against infections and cancers
publisher	Elsevier
publishDate	2023
url	http://eprints.sunway.edu.my/2696/ https://doi.org/10.1016/j.drudis.2023.103764
_version_	1802980694871244800
score	13.211869

Dual-action potential of cationic cryptides against infections and cancers

Similar Items